CD45 is also called leukocyte common antigen given its shared expression in the vast majority of cells of hematolymphoid lineage. The CD45 antibody used is a cocktail of 2 clones, PD7/26 (detects the CD45RB isoform), and 2B11 (detects a common CD45 protein). CD45 expression is very specific and quite sensitive for cells of hematolymphoid lineage, thus, distinguishing lymphoma/leukemia from other neoplasms. The main exception is classical Hodgkin Lymphoma, in which CD45 expression is absent.
No special preparation is needed for CD-45. Inform your doctor if you are on any medications or have any underlying medical conditions or allergies before undergoing CD-45. Your doctor depending on your condition will give specific instructions.
|UNISEX||All age groups||Test is positive if the conditions listed are detected|