CD45 is also called leukocyte common antigen given its shared expression in the vast majority of cells of hematolymphoid lineage. The CD45 antibody used is a cocktail of 2 clones, PD7/26 (detects the CD45RB isoform), and 2B11 (detects a common CD45 protein). CD45 expression is very specific and quite sensitive for cells of hematolymphoid lineage, thus, distinguishing lymphoma/leukemia from other neoplasms. The main exception is classical Hodgkin Lymphoma, in which CD45 expression is absent.
No special preparation is needed for Cd 45 Immunohistochemistry Biopsy Tissue. Inform your doctor if you are on any medications or have any underlying medical conditions or allergies before undergoing Cd 45 Immunohistochemistry Biopsy Tissue. Your doctor depending on your condition will give specific instructions.
|All age groups
|Test is positive if the conditions listed are detected