CD38 is a transmembrane protein that shows enzymatic activity involved in the production of calcium-mobilizing compounds and receptor activity involved in cellular adhesion and signaling in leukocytes. It is expressed in a variety of cell types including hematopoietic precursors, plasma cells, germinal center B cells (weakly), a subset of T and natural killer cells, erythrocytes, platelets, prostatic epithelium, and smooth and striated muscle cells. In some cases it may be a marker of activation. CD38 expression may be useful in the diagnosis of lymphoproliferative and plasma cell proliferative disorders. Determination of CD38 expression by flow cytometry has been used as a prognostic marker on chronic lymphocytic leukemia.
No special preparation is needed for CD 38. Inform your doctor if you are on any medications or have any underlying medical conditions or allergies before undergoing CD 38. Your doctor depending on your condition will give specific instructions.
|All age groups
|Test is positive if the conditions listed are detected