CD markers are expressed on specific hemotologic cells. Individual and a series of IHC markers can be run on unknown cells and presence or absence of the antigen can help to characterize the cell of interest. CD34 is 115-kD membrane-associated antigen found on human hematopoietic progenitor cells and vascular endothelial cells. In normal tonsil sections, antibodies to CD34 strongly stain vascular endothelial cells. Diagnostically, CD34 is used as a marker of immaturity in the setting of acute myeloid leukemia or B cell lymphoblastic leukemia. It is also useful in the classification of spindle cell neoplasms (gastrointestinal stromal tumors, solitary fibrous tumors, and angiosarcomas are often positive).
No special preparation is needed for Cd 34 Immunohistochemistry Biopsy Tissue. Inform your doctor if you are on any medications or have any underlying medical conditions or allergies before undergoing Cd 34 Immunohistochemistry Biopsy Tissue. Your doctor depending on your condition will give specific instructions.
Gender | Age groups | Value |
UNISEX | All age groups | Test is positive if the condition listed are detected |