The protein encoded by this gene is a surface antigen found on all peripheral blood T-cells. The encoded protein interacts with LFA3 (CD58) on antigen presenting cells to optimize immune recognition. CD2 is a pan T-cell antigen, expressed on normal and neoplastic T cells and natural killer cells. In normal tonsil, the T cells predominate in interfollicular regions. CD2 immunostaining is useful in determining T-cell lineage in cases of T-cell lymphoma. CD2 is a specific marker for T cells and NK cells, and can therefore be used in immunohistochemistry to identify the presence of such cells in tissue sections. The great majority of T cell lymphomas and leukaemias also express CD2, making it possible to use the presence of the antigen to distinguish these conditions from B cell neoplasms.
No special preparation is needed for CD 2 T Cell Marker Immunohistochemistry. Inform your doctor if you are on any medications or have any underlying medical conditions or allergies before undergoing CD 2 T Cell Marker Immunohistochemistry. Your doctor depending on your condition will give specific instructions.
|UNISEX||All age groups||Test is positive if the conditions listed are detected|