The B-cell marker, CD19, is expressed in the B-cell lineage from pre-B cell stage up to mature post-germinal center B cells, and is absent in plasma cells and most plasma cell neoplasms. With the exception of some follicular dendritic cells and rare aberrant expression in carcinomas, CD19 is specific for the B-cell lineage. CD19 is expressed by normal and neoplastic B cells but is not expressed by T cells, monocytes, or granulocytes. CD19 protein appears early during B-cell maturation and is found during all stages of B-cell maturation, including plasma cells. CD19 is useful as an additional marker of B cell lineage in leukemias and lymphomas. Expression of CD19 may be seen in some acute myeloid leukemias.
No special preparation is needed for IHC Marker CD 19 Immunohistochemistry Biopsy Tissue. Inform your doctor if you are on any medications or have any underlying medical conditions or allergies before undergoing IHC Marker CD 19 Immunohistochemistry Biopsy Tissue. Your doctor depending on your condition will give specific instructions.
|UNISEX||All age groups||Test is positive if the conditions listed are detected|