In normal lymphoid tissues, CD123 is expressed in plasmacytoid monocytes and mast cells in interfollicular regions. In bone marrow, it is expressed in hematopoietic precursors, mast cells, and megakaryocytes. CD123 is part of the IL3 receptor complex, involved in cellular growth and differentiation. Certain reactive lymph nodes show increased numbers of plasmacytoid monocytes, eg, Kikuchi lymphadenitis. CD123 is characteristically expressed in blastic plasmacytoid dendritic cell neoplasm, aiding in its distinction from acute monocytic leukemia.
No special preparation is needed for IHC Marker CD 123 Immunohistochemistry Bone Marrow. Inform your doctor if you are on any medications or have any underlying medical conditions or allergies before undergoing IHC Marker CD 123 Immunohistochemistry Bone Marrow. Your doctor depending on your condition will give specific instructions.
|UNISEX||All age groups||Test is positive if the conditions listed are detected|