KIT (CD117) membrane protein is a type III tyrosine kinase growth factor receptor for stem cell factor, also known as mast cell growth factor. It is expressed in mast cells, melanocytes, and interstitial cells of Cajal. KIT is expressed in various epithelia (breast, sweat glands and salivary glands, renal tubular cells, thyroid follicular cells), testicular and ovarian interstitial cells, neurons of the central nervous system, immature myeloid cells, and trophoblastic cells. KIT staining is useful in the diagnosis of gastrointestinal stromal tumors, germ cell tumors, mast cell disorders and acute myeloid leukemias.
No special preparation is needed for Cd 117 Immunohistochemistry Biopsy Tissue. Inform your doctor if you are on any medications or have any underlying medical conditions or allergies before undergoing Cd 117 Immunohistochemistry Biopsy Tissue. Your doctor depending on your condition will give specific instructions.
|All age groups
|Test is positive if the conditions listed are detected