CD103, also known as integrin alpha E, is an integrin subunit protein, which is widely expressed on T cells. CD103 is a useful diagnostic tool in the diagnosis of hairy cell leukemia. CD103 antibody recognizes the integrin subunit CD103 cell surface antigen, which is characteristically expressed in hairy cell leukemia (HCL), a B-cell lymphoproliferative disorder. CD103 EP206 has demonstrated reactivity in FFPE (formalin-fixed paraffin-embedded) tissue, eliminating the need for flow cytometric analysis or frozen section IHC, making it a valuable addition to an immunohistochemistry (IHC) panel for the diagnosis of HCL. Other antibodies that have been used in conjunction with CD103 for the detection of HCL include CD25, TIA-1, DBA44 and CD11c. Intraepithelial CD8 (+) tumorinfiltrating lymphocytes (TIL) that express CD103 have been shown to be strongly associated with patient survival in high-grade serous ovarian cancer.
No special preparation is needed for CD 103 Count Immunohistochemistry Biopsy Tissue. Inform your doctor if you are on any medications or have any underlying medical conditions or allergies before undergoing CD 103 Count Immunohistochemistry Biopsy Tissue. Your doctor depending on your condition will give specific instructions.
|UNISEX||All age groups||Test is positive if the conditions listed are detected|