CD10 is a cell surface glycoprotein present on bone marrow B precursors (hematogones) and myeloid cells (including neutrophils), follicle center B cells, and a subset of follicular T helper cells. CD10 is also expressed in the brush border of the upper part of the intestinal tract, bile canaliculi, kidney (glomerular and proximal tubular cells), pulmonary alveolar cells, myoepithelial cells of breast, prostate glandular cells, placental trophoblastic cells, endometrial stromal cells, some endothelial cells, and a minority of (myo-)fibroblasts (stromal cells). CD10 is most useful in the diagnosis of B-precursor-acute lymphoblastic leukemia, Burkitt lymphoma, and lymphomas of follicle cell center origin (follicular lymphoma, subset of large B-cell lymphomas).
No special preparation is needed for Cd 10 Calla Immunohistochemistry Biopsy Tissue. Inform your doctor if you are on any medications or have any underlying medical conditions or allergies before undergoing Cd 10 Calla Immunohistochemistry Biopsy Tissue. Your doctor depending on your condition will give specific instructions.
|All age groups
|Positive in Acute Lymphoblastic Lymphoma, marker for Myoeithelial cells