Bone Profile

Bone profile test measures the levels of calcium, albumin, and alkaline phosphate (ALP). Bone profile test is used for the assessment of bone diseases like osteoporosis, osteopenia, parathyroid disorders, osteomalacia, osteolytic lesions secondary to metastasis, Paget’s disease, etc.

Osteoporosis:

This is a type of bone disease where the bones become weak and brittle. This condition is due to an imbalance between the breakdown and rebuilding of bone tissues. This is mostly disturbed due to hormonal changes or dietary changes. During these changes, the bone may lose some of the minerals that contribute to its density and strength.

Osteopenia:

This is a condition in which the bone density is decreased.

Parathyroid disorders:

Parathyroid disorders may lead to abnormal levels of calcium in the blood that may lead to brittle bones, kidney stones, tiredness, weakness, etc.

Osteomalacia:

Osteomalacia is caused due to deficiency of vitamin D and calcium which results in softening of bones.

Osteolytic lesions:

Osteolytic lesions are the symptoms of specific diseases like breast cancer, multiple myelomas, etc. Osteolytic lesions are the softened section of the bones.

Paget’s Disease: Paget’s Disease is a bone disorder in which old bone tissues are gradually replaced by new bone tissues. This may lead to fragile bones.

Test parameters:

• Albumin
• Alkaline Phosphate (ALP)
• Calcium

Albumin:

Albumin is a globular protein made by the liver. This helps in the binding of water, cations like calcium (ca2+), Sodium (Na+), and potassium (K+), fatty acids, bilirubin, hormones, thyroxine, etc.

Alkaline Phosphatase (ALP):

Alkaline Phosphatase is an enzyme found in various tissues throughout the body. The highest concentrations of alkaline phosphatase are found in bone and liver.

Calcium: Calcium is useful in building bones and maintaining their health. 99% of calcium in our body is in our bones and teeth.

Why this test is performed?

This test may be recommended to you to check your bone health. This test is also recommended if you experience certain symptoms like chronic bone pain, joint pain, deformed bones, bones that are brittle or break easily, weakness, tiredness, muscle weakness, vomiting, dehydration, constipation, nausea, polyuria, release of gastrin, etc. If you had a fracture recently this test may be performed to assess the strength of your bones. This test is also recommended to evaluate the effectiveness of the treatment given for any of your bone diseases.

No specific preparation is required for this test.