Bone marrow MPO (Myeloperoxide) staining is used for diagnosing any bone marrow related disorders. The myeloperoxidase stain distinguishes between the immature cells in acute myeloblastic leukemia (cells stain positive) and those in acute lymphoblastic leukemia (cells stain negative). Useful in differentiating hematopoietic cells for leukemia. This test also helps in a number of conditions like leukemia (cancer of blood-forming cells), lymphoma (blood cancer of lymphatic system), multiple myeloma (a type of blood cancer related to lymphomas), anemia (deficiency of red blood cells), pancytopenia(deficiency of red blood cells, white blood cells and platelets), etc.
Myeloperoxide (MPO) is a peroxidase enzyme mostly present in neutrophil granulocytes. It is a lysosomal protein which is stored in azurophilic granules of neutrophils. Myeloperoxide is a heme pigment which gives green color in secretions rich in neutrophils, such as pus and some form of mucus. Myeloperoxidase detects granulocytes and monocytes in blood and precursors of granulocytes and monocytes in blood and precursors of granulocytes in the bone marrow.
Bone marrow is a soft tissue present inside the bones that help in the formation of blood cells like red blood cells (RBC), white blood cells (WBCs), and platelets. Red blood cells help in carrying of oxygen and nutrients, white blood cells help to fight infection and platelets help in clotting of the blood.
This test may be recommended to you if you are suspected to have a bone marrow related disorder. This test is also performed to find out the stage of a disease. This test also used to evaluate the effectiveness of the treatment given. If your complete blood count shows the abnormal levels of red blood cells or white blood cells then this test is recommended to find out the cause. This test is also recommended to you if you experience certain conditions like anemia, infections, leukemia, other blood cancers or disorders, etc.
Inform your doctor if you are on any medications, have any allergies or underlying medical conditions before your Bone Marrow Mpo Stain Microscopy Bone Marrow. Your doctor will give specific instructions depending on your condition on how to prepare for Bone Marrow Mpo Stain Microscopy Bone Marrow.
No specific preparation is required for this test.
The normal test results may vary depending on age, health history, medical condition, etc.
The test results can be interpreted only by your doctor. Hence consult your doctor soon after receiving your lab reports for further diagnosis or medical intervention.
|UNISEX||All age groups||Positive Staining in Acute Myeloid Leukemia|