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Practo

Diagnostic Tests

Biopsy Immunoflourescence Skin Tissue

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Biopsy Immunoflourescence Skin Tissue

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What is this test?

Biopsy Immunofluorescence Skin Tissue test is useful in identifying the antibodies and immunoglobulins produced during allergies or autoimmune diseases like systemic lupus, dermatitis, etc. The test is done on a skin sample of an individual.

What is Biopsy Skin?

The process of collecting a small sample of tissue using a fine needle or an incision (cut) is called a biopsy. In this process, a small fragment of the skin tissue is collected. A biopsy can be done to collect a tissue sample from various sites/internal organs like kidney, liver, skin, bone, bone marrow, lungs, urinary and reproductive tissue, sites of suspected tumors like breast, etc. Tissue biopsy is useful in examining any changes which may have occurred to the tissue during any conditions like tumors, cancers, bacterial or viral infections, autoimmune diseases like vasculitis, bullous pemphigoid, contact dermatitis, systemic lupus, scleroderma, etc.

What is immunofluorescence skin?

This is a type of laboratory technique used to identify specific antigen and antibodies present in the given tissue sample. The tissue sample is processed and stained with specific fluorescent dyes to visualize the target proteins and molecules. Some of the proteins which are visualized in this technique are IgG, IgM, IgA, C3 (complement proteins), etc. The tests are very sensitive and can be used to identify, estimate the progress of the treatment and the disease as well.

Why this test is recommended?

This test is recommended by the doctor if you experience symptoms like unexplained lesions, blisters on the skin, rashes, itchy skin, redness, burning sensation of the skin, localized discolorations (darkening or white patches of skin), etc.

This test can also be recommended if an individual is suffering from diseases like tumors, cancers, bacterial or viral infections, autoimmune diseases like vasculitis, bullous pemphigoid, contact dermatitis, systemic lupus, scleroderma, arthritis, etc.

Test Preparation

Inform your doctor if you are on any medications, have any allergies or underlying medical conditions before your Biopsy Immunoflourescence Skin Tissue. Your doctor will give specific instructions depending on your condition on how to prepare for Biopsy Immunoflourescence Skin Tissue.

Understanding your test results

The normal test results may vary depending on age, health history, medical condition, etc.

Positive test results may indicate the presence of any antibodies related to tissue abnormalities or any of the autoimmune diseases.

The test results may be negative if there are no antibodies or antigens related to the suspected disease condition and might require further diagnostic tests.

Please consult your health provider after receiving your lab reports for further diagnosis or medical intervention based on your clinical conditions.

GenderAge groupsValue
MALEAll age groupsThe observations depend on the type of skin disease
FEMALEAll age groupsThe observations depend on the type of skin disease
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