Diagnostic Tests

Benzodiazepines Quantitative Random Urine


Benzodiazepines Quantitative Random Urine

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What is this test?

Benzodiazepines Quantitative Random Urine measures the levels of a class of benzodiazepines medicines in the urine by collecting a random urine sample. This test is used in the assessment of benzodiazepines use and overdose.

What are Benzodiazepines?

Benzodiazepines are a group of medicines that are used to depress the central nervous system. These medicines work by binding to certain chemicals in the brain and helps in relieving the symptoms. It is used in the treatment of anxiety disorders. It helps uneasiness, difficulty in sleeping, prevent seizures, relax muscle spasms, etc. These medicines are broadly classified into four groups namely antianxiety medicines, muscle relaxants, antiseizure medicines, and sedative-hypnotic (sleeping pills).

Benzodiazepines that are commonly used for the treatment of anxiety disorders, seizures, and muscle spasms are clonazepam, diazepam, lorazepam, alprazolam, chlordiazepoxide, oxazepam, etc. Commonly used sedative-hypnotic (sleeping pills) are estazolam, triazolam, temazepam, flurazepam, etc. These medicines are also abused or sometimes used illegally. It can be habit forming and chronic abuse leads to addiction. Checking the levels of benzodiazepines in the urine helps in the assessment of benzodiazepines use and overdose.

Why this test is performed?

This test is performed for the assessment of benzodiazepines use and overdose. Your doctor may ask you to perform this test to monitor the benzodiazepines levels in the urine and to detect high or low concentrations. You may be advised to perform this test if you experience any signs and symptoms of benzodiazepines overdose such as altered mental status, coma, drowsiness, slurred speech, low blood pressure, unconsciousness, sluggishness, abnormal breathing, etc. However, your doctor may ask to perform a few more additional tests along with this test to check whether these symptoms are due to benzodiazepines overdose or due to any other cause.

This test is also performed in individuals who are not on therapy with benzodiazepines if your doctor suspects you are abusing the medicines illegally or without a prescription.


Older adults and individuals with liver disease may give false positive or false negative results.

Test Preparation

Inform your doctor if you are on any medications, have any allergies or underlying medical conditions before your Benzodiazepines Quantitative Random Urine. Your doctor will give specific instructions depending on your condition on how to prepare for Benzodiazepines Quantitative Random Urine.

No specific preparation is required for this test. However, if you are on therapy with benzodiazepines medicines your healthcare provider may ask you information regarding the dosage timing and formulation type of the medicine to decide the proper timing of sample collection.

Understanding your test results

The test results may be different depending on gender, age, health conditions, and other factors.

If the test results show higher benzodiazepines levels than the normal range in the urine it may indicate benzodiazepines overdose. Individuals receiving benzodiazepines therapy, the higher levels may indicate a need for dose adjustment. Individuals who are not on therapy with benzodiazepines a positive result may indicate benzodiazepines use which can be an abuse.

If the test results show very lower benzodiazepines levels in the urine in individuals receiving benzodiazepines therapy, it may indicate a problem with the elimination of medicines. Individuals who are not on therapy with benzodiazepines a negative result may indicate no use of benzodiazepines or abuse.

Based on the test results, your doctor may advise appropriate medical treatments or further diagnostic tests.

GenderAge groupsValue
UNISEXAll age groupsPositive in Benzodiapines exposure
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