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ACE CSF

Also known as Angiotensin Converting Enzyme Csf
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What is this test?

Angiotensin Converting Enzyme CSF test is used to measure the angiotensin-converting enzyme in your cerebrospinal fluid. This test helps in diagnosing neurosarcoidosis.

What is Neurosarcoidosis?

Sarcoidosis is a type of inflammatory disease which affects multiple organs in the body, mostly the lungs and lymph glands. In the case of sarcoidosis, abnormal masses or nodules which are called granulomas. There will be inflammation of tissues in certain organs of the body. Neurosarcoidosis is an inflammation that affects the nervous system. There will be inflammation of the brain or spinal cord. In very rare cases with sarcoidosis will develop neurosarcoidosis. Neurosarcoidosis is also called as neurologic sarcoidosis.

The symptoms of neurosarcoidosis vary according to the part which is getting affected. If the brain or cranial nerves are affected the symptoms experienced are headaches, loss of hearing, confusion, seizures, dementia, inability to taste or smell, speech difficulties, irritability, hallucinations, speech difficulties, psychiatric issues, double vision, palsy in the facial muscles, etc. If the peripheral nerves are affected the symptoms observed are weak muscles, tingling, and numbness, inability to move some parts of the body. If the pituitary gland is affected then severe tiredness, extreme thirst, need to urinate frequently, menstrual cycle changes, etc are seen.

Why this test is performed?

This test may be recommended if you experience symptoms like seizures, dementia, headaches, loss of hearing, confusion, inability to taste or smell, speech difficulties, irritability, hallucinations, speech difficulties, psychiatric issues, double vision, palsy in the facial muscles, weak muscles, tingling and numbness, inability to move some parts of the body, severe tiredness, extreme thirst, need to urinate frequently, menstrual cycle changes, etc.

Test Preparation

Inform your doctor if you are on any medications, have any allergies or underlying medical conditions before your ACE CSF. Your doctor will give specific instructions depending on your condition on how to prepare for ACE CSF.

No specific preparation is required for this test.

Understanding your test results

The reference range may vary depending on gender, age, health history, health condition, etc.

If your test results are higher than the normal reference range it may indicate neurosarcoidosis.

GenderAge groupsValue
MALEAll age groups< 15 U/L
FEMALEAll age groups< 15 U/L
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