Adrenocorticotropic hormone (ACTH or corticotropin) is a 39 amino acid polypeptide hormone synthesised from pre-opiomelanocortin (POMC). It is secreted from corticotropes in the anterior lobe of the pituitary gland in response to a corticotropin-releasing hormone. Clinical manifestations of immediate hypersensitivity (allergic) diseases are caused by the release of proinflammatory mediators (histamine, leukotrienes, and prostaglandins) from immunoglobulin E (IgE)-sensitized effector cells (mast cells and basophils) when cell-bound IgE antibodies interact with allergen.
No special preparation is needed for Allergy Acth Radio Immunoabsorbent. Inform your doctor if you are on any medications or have any underlying medical conditions or allergies before undergoing Allergy Acth Radio Immunoabsorbent. Your doctor depending on your condition will give specific instructions.
|UNISEX||All age groups||Increased IgE (>100kU/l) is seen if the person is allergic to the specific substance|