Aldolase is necessary for glycolysis in muscle as a rapid response pathway for production of adenosine triphosphate, independent of tissue oxygen. Aldolase catalyses the conversion of fructose 1,6-diphosphate into dihydroxyacetone phosphate and glyceraldehyde 3-phosphate, an important reaction in the glycolytic breakdown of glucose to lactate in muscle. Aldolase is a tetramer whose primary structure depends upon the tissue from which it was synthesized (liver, muscle, brain). The brain form of aldolase has, because of its preponderance in white cells, been suggested to be a leukemia marker, but this is not confirmed.
Inform your doctor if you are on any medications, have any allergies or underlying medical conditions before your Aldolase. Your doctor will give specific instructions depending on your condition on how to prepare for Aldolase.
Fasting of 6 hours is required before this test.
|UNISEX||All age groups||1 to 7.5 units per liter|