This test is used to test the sensitivity of the acid-fast bacilli (Mycobacterium tuberculosis) against certain types of antibiotic medicines. This test is useful in adjusting and providing effective treatment for individuals suffering from tuberculosis. This test can also be done to check whether the bacteria has developed any resistance towards the medicine or not.
What is TB?
Tuberculosis TB is a bacterial infection caused by Mycobacterium tuberculosis MTB. Generally, TB affects the lungs and sometimes it can also affect other organs and parts of the body. The disease can spread through the air from one person to another if exposed to cough, sneeze from the individual. Individuals who are suffering from TB experience symptoms such as cough which lasts more than 2-3 weeks, cough with blood, chest pain, difficulty in breathing, weight loss, fever, night sweats, etc.
What is Pyrazinamide?
Pyrazinamide is an antitubercular medicine which helps to treat tuberculosis and reduces the spread of infection. It should be taken with other medicines to prevent the spread of infection. This medicine is not recommended in patients with liver impairment or acute gout.
What is the broth dilution method?
This is a type of laboratory procedure used to test the sensitivity of the bacteria towards specific antibiotics and antibiotic combinations. A standardized concentration of bacterial culture is tested against nutrient media containing different concentrations or combinations of antibiotics to know the effective combination or concentration in which the antibacterial activity is the highest.
Why this test is recommended?
This test is performed to check the sensitivity of antibiotics towards tuberculosis bacteria in a tissue sample of an individual. The doctor may ask you to undergo this test if you are suffering from symptoms such as headaches, dizziness, joint pains, long-lasting cough, chest pain, difficulty in breathing, weight loss, fever, abdominal distension, etc.
If you are on treatment for tuberculosis, then the doctor may ask you to perform this test to evaluate and to check the effectiveness of the treatment and to check whether the bacterium has infected other internal organs or has developed resistance to TB drugs such as rifampicin. Mostly, this test is done along with other tests to confirm the diagnosis and to modify the treatments if necessary.
Inform your doctor if you are on any medications, have any allergies or underlying medical conditions before your Afb Mtb - Pyrazinamide Broth Dilution Infected Tissue. Your doctor will give specific instructions depending on your condition on how to prepare for Afb Mtb - Pyrazinamide Broth Dilution Infected Tissue.
No specific preparations required for this test.
The test results may be different depending on gender, age, health conditions, and other factors.
Negative test results indicate that the medicine is not effective in treating the infection or the bacteria has developed resistance towards the particular medicine.
Positive test results indicate that the bacteria is sensitive towards the medicine and the medicine is effective in killing the bacteria. Based on the test results your doctor will suggest you the appropriate treatments and dose adjustments.
|MALE||All age groups||A result where the drug is sensitive indicates that the patient responds to this antibiotic|
|FEMALE||All age groups||A result where the drug is sensitive indicates that the patient responds to this antibiotic|