Diagnostic Tests

Afb Mtb - Moxifloxacin Antibacterial Gradient Infected Tissue


Afb Mtb - Moxifloxacin Antibacterial Gradient Infected Tissue

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What is this test?

Moxifloxacin is a bacteriacidal fluoroquinolone antibiotic that is effective against gram-positive and gram-negative organisms as well as other infectious agents, including Mycobacterium tuberculosis. It is used to treat a broad range of infections, including pneumonia, multi-drug resistant tuberculosis, and endocarditis. Moxifloxacin increases the risk of tendinitis and tendon rupture, and is not recommended for children under the age of 18. A gradient strip is a reagent strip that contains a predefined concentration gradient of a specific antibiotic or combination of antibiotics that is used for antimicrobial susceptibility testing (AST) and antimicrobial resistance detection (ARD). For AST, the result is reported in terms of the minimum inhibitory concentration (MIC) of a specific antimicrobial that prevents the visible growth of bacteria. In LOINC, the "Gradient strip" method is used for AST gradient strips that result in an MIC result. For ARD, the result is reported as the presence or absence of a specific enzyme or other mechanism that confers resistance, which is determined based on comparing the inhibitory concentration (IC) of a specific antimicrobial with the IC of that antimicrobial plus a resistance inhibitor. In LOINC, the "Gradient strip ARD" method is used for ARD gradient strips, which are not intended for determining individual MIC values. A small strip is impregnated with an antimicrobial drug that has an increasing concentration from one end of the strip to another. The concentrations of the antibiotic are marked along the strip. The strip is placed on the agar surface that has been inoculated by a specified concentration of the isolated organism being tested. The minimum inhibitory concentration (MIC) of antibiotics, antifungals, or antimycobacterials is determined by the intersection of the border where microbial growth is inhibited and the concentration of antimicrobial designated on the strip.[CLSI, Methods for Determining Bactericidal Activity of Antimicrobial Agents.

Also known as Acid Fast Bacilli MTb - Moxifloxacin Antibacterial Gradient Infected Tissue, AFB Sensitivity - Moxifloxacin Antibacterial Gradient Infected Tissue.

Test Preparation

No special preparation is needed for Afb Mtb - Moxifloxacin Antibacterial Gradient Infected Tissue. Inform your doctor if you are on any medications or have any underlying medical conditions or allergies before undergoing Afb Mtb - Moxifloxacin Antibacterial Gradient Infected Tissue. Your doctor depending on your condition will give specific instructions.

Understanding your test results

GenderAge groupsValue
UNISEXAll age groupsA result where the drug is sensitive indicates that the patient responds to this antibiotic
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