Testing for drug susceptibility to ethionamide, a crucial part of second line anti-tuberculosis therapy, is problematic as the difference characterizing drug resistance or susceptibility is small. Moreover, the minimum inhibitory concentration (MIC) is very near to the therapeutic index. Inspite of the importance of ethionamide in the treatment of MDR-TB, there are only a few reports on the drug susceptibility testing of this agent. The gold standard of drug susceptibility testing against anti-tuberculosis agents is the proportion method that uses a single critical concentration of drugs to determine resistance or susceptibility. However, the thermolabile nature of ethionamide may play a role in reducing the potency of the drug during inspissation of the drug containing medium. Deterioration of the drug during prolonged incubation period required for M. tuberculosis can also be crucial.
No special preparation is needed for Acid Fast Bacilli MTb - Ethionamide Antibacterial Gradient Infected Tissue. Inform your doctor if you are on any medications or have any underlying medical conditions or allergies before undergoing Acid Fast Bacilli MTb - Ethionamide Antibacterial Gradient Infected Tissue. Your doctor depending on your condition will give specific instructions.
|All age groups
|A result where the drug is sensitive indicates that the patient responds to this antibiotic