Activated Partial Thromboplastin time test is done on a sample of blood from an individual to check the time required for the blood to clot. Increased blood clotting time is often associated with blood loss and bleeding disorders.
What is Activated Partial Thromboplastin Time?
The partial thromboplastin is formed in the blood clotting pathway in the presence of blood clotting factors IX, X1, and factor XII. The test is used to check the function of these clotting factors. These blood clotting factors would be reduced or absent in individuals with bleeding disorders like haemophilia, leukaemia, liver damage or disease, use of certain anti-coagulant medicines like warfarin, heparin, etc. A person is said to have a bleeding disorder If the sample of blood is taking longer-than-normal time for the formation of a clot.
Why this test is recommended?
This test is recommended by the doctor if a person experiences symptoms like frequent bleeding episodes like nose bleeds, easy bruising, bleeding from gums, blood in stools, abnormal periods in women, painful and swollen joints, etc.
This test is recommended by the doctor if a person is suffering from diseases or disorders associated with blood like vitamin K deficiency, leukaemia (cancer affecting blood and bone marrow), haemophilia, clotting factor deficiency, etc. This test can also be advised by the doctor if the person is undergoing anticoagulant therapy.
Precautions:
Drugs such as Vitamin supplements, anti-coagulant medicines like heparin etc may affect the test results. Hence, you are advised to inform your doctor about all your current medications before undergoing this test.
Inform your doctor if you are on any medications, have any allergies or underlying medical conditions before your aPTT. Your doctor will give specific instructions depending on your condition on how to prepare for aPTT.
Inform your doctor about the use of any medicines or underlying medical conditions to your doctor. This test is done after you fast (without eating anything) for a whole night or for 8 to 12 hours. Usually, the blood is drawn in the morning after overnight fasting.
Normal test results may vary based on gender, age, health condition or history of the individual.
The partial thromboplastin time is measured in seconds. If the aPTT time is greater than the normal reference range the individual may be suffering from diseases affecting blood and blood clotting like vitamin K deficiency, deficiency of blood clotting factors, cancers associated with blood and bone marrow, etc.
Please consult your physician with the test results. Your doctor may recommend appropriate treatment or further diagnostic tests if necessary.
Gender | Age groups | Value |
MALE | All age groups | 28 - 38 seconds |
FEMALE | All age groups | 28 - 38 seconds |