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Zypara 500 MG Tablet
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Zypara 500 MG Tablet

Manufactured byCadila Pharmaceuticals Ltd.
ContainsPyrazinamide
Description
Zypara 500 MG Tablet is an antitubercular medicine which helps to treat tuberculosis and reduces the spread of infection. It should be taken with other medicines to prevent the spread of infection. This medicine is not recommended in patients with liver impairment or acute gout.
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Side effectsConcernsUsageRelated products

Substitutes

List of substitutes for Zypara 500 MG Tablet

Antizide 500 MG Tablet
Strides Shasun Ltd.
Macrozide 500 MG Tablet
Macleods Pharmaceuticals Pvt. Ltd.
Pyrazinamide 500 MG Tablet
Zydus Cadila
Pyzina 500 MG Tablet
Lupin Ltd.
PZIDE 500 MG TABLET
Cadila Pharmaceuticals Ltd.

Side effects

Major & minor side effects for Zypara 500 MG Tablet

  • Joint pain
  • Loss of appetite
  • Unusual tiredness and weakness
  • Yellow colored eyes or skin
  • Itching
  • Skin rash
  • Photosensitivity
  • Nausea and Vomiting

Uses of Zypara 500 MG Tablet

What is it prescribed for?

  • Tuberculosis
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with known allergy to pyrazinamide or any other inactive ingredient present in the formulation.

Severe liver impairment

This medicine is not recommended for use in patients suffering from a severe liver impairment or an acute liver disease due to the increased risk of worsening of the patient's condition.

Acute Gout

This medicine is not recommended for use in patients with increased uric acid levels or acute gout due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Impaired liver function

This medicine may cause liver injury. The baseline of liver function tests should be obtained before initiating the treatment. Any signs of elevated liver enzymes should be reported to the doctor.

Diabetes

This medicine should be used with caution in patients with diabetes. Close monitoring of blood glucose levels is necessary. Any signs of altered glucose levels should be reported to the doctor.

Drug-resistance

Usage of this medicine without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that is drug resistant.

Impaired kidney function

This medicine should be used with caution in patients with kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function tests, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Missed Dose

Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Methotrexate

Cholera Vaccine

Lomitapide

Efavirenz

Cyclosporine

Mipomersen

cannabidiol

Disease interactions

Gout

This medicine is not recommended for use in patients with acute gout conditions serum uric acid should be frequently monitored. An alternative treatment option should be considered based on clinical conditions.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take this medicine as advised by the doctor. Do not take in larger amounts than advised. It is advised to take this medicine at the same time every day. Do not stop taking the medicine without consulting your doctor. Ensure that the course of treatment is completed to prevent the spread of infection. Consult the doctor if you experience any undesirable effects.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by altering the pH in the cell and stops its growth of the bacteria.
Legal Status

Approved

Approved

Unknown

Approved

Classification

Category

Antituberculosis agents

Schedule

Schedule H

Zinamide 500mg Tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2020 [cited 29 January 2020]. Available from:

https://www.medicines.org.uk/emc/medicine/28620

Pyrazinamide: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2020 [cited 29 January 2020]. Available from:

https://medlineplus.gov/druginfo/meds/a682402.html

DailyMed - Pyrazinamide tablet [Internet]. Dailymed.nlm.nih.gov. 2020 [cited 29 January 2020]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=257bd8cf-74d7-45db-bf25-354a8d26634e
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Information on this page was last updated on 24 Feb 2020

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