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Zupion-SR Tablet
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Zupion-SR Tablet

Manufactured byINTAS PHARMACEUTICALS LTD
ContainsBupropion
Description
Zupion-SR Tablet is used in the treatment of depression, smoking cessation, and seasonal affective disorder. This medicine is not recommended for use in patients less than 18 years of age.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Zupion-SR Tablet

  • Anxiety
  • Irritability
  • Restlessness
  • Irregular heartbeat
  • Trouble sleeping
  • Headache
  • Skin Rash
  • Ringing or buzzing in the ears
  • Confusion

Uses of Zupion-SR Tablet

What is it prescribed for?

  • Major depressive disorder
  • Seasonal Affective Disorder
  • Smoking cessation
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as seizures, dizziness, mood and behavioral changes, and fainting. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women. All the risks and benefits should be discussed with the doctor before using this medicine. Your doctor may advise you to discontinue the drug or to discontinue breastfeeding based on your clinical condition

Allergy

This medicine is not recommended for use in patients with a known allergy to bupropion or any other inactive ingredients present along with it.

Monoamine oxidase inhibitors (MAOI)

This medicine is not recommended for use in patients taking monoamine oxidase inhibitors (MAOI) due to the increased risk of serious and life-threatening side effects. A time gap of at least 14 days should be maintained between the administration of these medicines.

Anorexia nervosa and Bulimia

This medicine is not recommended for use in patients with a current or history of eating disorders such as anorexia nervosa or bulimia due to the risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women. All the risks and benefits should be discussed with the doctor before using this medicine. Your doctor may advise you to discontinue the drug or to discontinue breastfeeding based on your clinical condition
General warnings

Liver impairment

This medicine should be used with caution in patients with an impaired liver function due to the increased risk of severe adverse effects. Close monitoring of liver function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Kidney impairment

This medicine should be used with caution in patients with an impaired kidney function due to the increased risk of severe adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Weight Loss

Usage of this medicine may increase the risk of weight loss which may be undesirable in patients suffering from anorexia, malnutrition, excessive weight loss, etc. Regular monitoring of weight change is necessary while receiving this medicine.

Driving or Operating machinery

Use of this medicine may cause dizziness, weakness, etc. in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Use in children

This medicine is not recommended for use in patients less than 18 years of age since the safety and efficacy of use are not clinically established.

Suicidal tendencies

This medicine should be used with caution due to the increased risk of suicidal tendencies. This risk is especially higher in young patients. Patients should be closely monitored for any change in mood or behavior. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Hypertension

This medicine may increase the blood pressure levels and therefore should be used with caution in patients with hypertension (high blood pressure) due to the increased risk of worsening of the patient's condition. Close monitoring of blood pressure levels, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Seizure disorder

This medicine should be used with extreme caution in patients with seizure disorder or conditions that may increase the risk of seizures such as severe head injury, CNS tumor, CNS infection, severe stroke, etc. due to the increased risk of worsening of the patient's condition. Replacement with a suitable alternative may be necessary based on the clinical condition.

Missed Dose

Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as seizures, dizziness, mood and behavioral changes, and fainting. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Deflazacort

Amoxapine

Doxepin

Amantadine

Codeine

Aripiprazole

Disease interactions

Liver Disease

This medicine should be used with caution in patients suffering from liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Seizure disorders

This medicine should be used with caution in patients with a history of seizure disorder or a family history of seizures since it may worsen the patient's condition. Report any unusual symptoms to the doctor immediately. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Angle Closure Glaucoma

This medicine should be used with caution in patients with angle-closure glaucoma since it may increase the risk of a rise in intraocular pressure. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Psychosis

This medicine should be used with caution in patients with psychotic disorders since it may worsen the patient's condition. Report any unusual symptoms to the doctor immediately. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions

Urine test for Amphetamines

Report the use of this medicine to the doctor if you are undergoing this test. A false positive result may be obtained if this test is performed while taking this medicine. Do not stop the use of any medicine without consulting your doctor.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take this medicine with or without food. Do not take larger or smaller amounts than prescribed. Seek emergency medical treatment in case of any severe side effects. Ensure that the course of treatment is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
It works by increasing certain chemical substances in the brain which helps in maintaining the mental balance.
Legal Status

Approved

Unknown

Unknown

Approved

Classification

Category

Miscellaneous antidepressants, Smoking cessation agents

Schedule

Schedule H

Bupropion - DrugBank [Internet]. Drugbank.ca. 2018 [cited 14 September 2018]. Available from:

https://www.drugbank.ca/drugs/DB01156

[Internet]. Gsksource.com. 2018 [cited 14 September 2018]. Available from:

https://www.gsksource.com/pharma/content/dam/GlaxoSmithKline/US/en/Prescribing_Information/Wellbutrin_Tablets/pdf/WELLBUTRIN-TABLETS-PI-MG.PDF

Bupropion: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2018 [cited 14 September 2018]. Available from:

https://medlineplus.gov/druginfo/meds/a695033.html

Zyban 150 mg prolonged release tablets - Summary of Product Characteristics (SmPC) - (eMC) [Internet]. Medicines.org.uk. 2018 [cited 14 September 2018]. Available from:

https://www.medicines.org.uk/emc/product/3827/smpc#
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Information on this page was last updated on 27 Mar 2019

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