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Zoftagen 80 MG Injection

Manufactured byElder Pharmaceuticals Ltd.
ContainsGentamicin
Description

Zoftagen 80 MG Injection is a bactericidal antibiotic that is used to treat a variety of infections caused by the bacteria in different parts in the body such as bones, skin, urinary tract infections, etc. This medicine may increase the risk of kidney injury or hearing problems. This medicine is not recommended for use if you are known allergic to it.

Side effects

Major & minor side effects for Zoftagen 80 MG Injection

  • Abdominal pain
  • Agitation
  • Blurred vision
  • Changes in urine frequency
  • Hearing loss
  • Dizziness when getting up suddenly from a sitting position
  • Dry mouth
  • Fast heartbeat
  • Itching or rash
  • Increased salivation
  • Depression

Uses of Zoftagen 80 MG Injection

What is it prescribed for?

  • Bacteremia
  • Intraabdominal Infection
  • Bacterial Meningitis
  • Osteomyelitis
  • Skin and Soft tissue infections
  • Pyelonephriits
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed immediately after the administration of the dose.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before administering this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before administering this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to gentamicin, or any other inactive ingredients present along with the formulation.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before administering this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before administering this medicine.
General warnings

Kidney Diseases

This medicine should be used with caution in patients with a known history of an impaired kidney function due to the increased risk of severe adverse effects. Close monitoring of kidney function tests, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Neuromuscular disorders

This medicine is not recommended in patients with existing neuromuscular diseases like Parkinson's disease. Appropriate dose adjustments or replacement with a suitable alternative/Supplements might be required based on the clinical condition.

Drug-resistance

Usage of this medicine without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of developing of bacteria that are drug-resistant.

Missed Dose

Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low.

Overdose

Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Furosemide

Nonsteroidal anti-inflammatory drugs

Cephalosporins

Fenoprofen

Disease interactions

Dehydration

Consume an adequate amount of water to prevent kidney injury and hearing problem. Fluid status should be monitored closely in the patients with severe diarrhea and vomiting. Frequent monitoring of kidney function tests is necessary. Dose adjustments are to be made based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by inhibiting the protein synthesis which is essential for the bacteria to grow.
Legal Status

Approved

Unknown

Approved

Approved

Classification

Category

Aminoglycosides

Schedule

Schedule H

[Internet]. Accessdata.fda.gov. 2020 [cited 22 January 2020]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/062366s033lbl.pdf

Gentamicin 40 mg/ml Injection - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2020 [cited 22 January 2020]. Available from:

https://www.medicines.org.uk/emc/product/6531/smpc

Gentamicin - DrugBank [Internet]. Drugbank.ca. 2020 [cited 21 January 2020]. Available from:

https://www.drugbank.ca/drugs/DB00798

Gentamicin [Internet]. Pubchem.ncbi.nlm.nih.gov. 2020 [cited 21 January 2020]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/Gentamicin
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Information on this page was last updated on 10 Feb 2020

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.