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ZEOF-400 Tablet

Manufactured byZuventus Healthcare Ltd.
ZEOF-400 Tablet is an antibiotic used for the treatment of bacterial infections affecting your lungs, skin, and urinary tract (the kidneys, bladder etc). It works by stopping the growth of bacteria that causes infection. It is not effective against infections caused by viruses. ZEOF-400 Tablet can cause side effects like diarrhoea, stomach pain, headache, nausea, and vomiting. Consult your doctor if these side effects persist or become worse. Avoid activities that require mental focus like driving vehicles and operating machines as this medicine may cause dizziness. ZEOF-400 Tablet can be taken with or without food as prescribed by your doctor. Your doctor will determine the dose of this medicine based on your condition. Take this medicine at the same time every day for the ease of remembering. Complete the whole course of treatment for maximum benefit and to prevent the risk of re-infection. ZEOF-400 Tablet is not recommended for use if you are allergic to it. Avoid taking this medicine if you have tendinitis (a condition that causes swelling of the tissues that attach bones with muscles) or myasthenia gravis (a condition that causes severe weakness of the muscles under voluntary control). ZEOF-400 Tablet should be used with caution if you have liver or kidney problems. Report all your medicines to your doctor as they may interact with ZEOF-400 Tablet and cause side effects. If you are pregnant or are breastfeeding, consult your doctor before taking this medicine.

Side effects

Major & minor side effects for ZEOF-400 Tablet

  • Stomach pain
  • Headache
  • Black or tarry stools
  • Nausea and vomiting
  • Loose stools
  • Fever
  • Painful urination
  • Decreased appetite
  • Joint pain
  • Change in taste
  • Excessive air or gas in stomach
  • Runny nose
  • Dizziness

Uses of ZEOF-400 Tablet

What is it prescribed for?

  • Urinary Tract Infection
  • Pyelonephritis
  • Urethritis
  • Cystitis
  • Community-Acquired Pneumonia
  • Bronchitis
  • Skin and soft tissue infections
Read More

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The time taken for ZEOF-400 Tablet to show its effect is not known.
  • How long do the effects of this medicine last?
    ZEOF-400 Tablet may remain active in your body for 12 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Avoid intake of alcohol while on treatment with ZEOF-400 Tablet. It may lead to increased drowsiness and dizziness.
  • Is this a habit forming medicine?
    No habit-forming tendency has been reported for ZEOF-400 Tablet.
  • Can this medicine be taken during pregnancy?
    ZEOF-400 Tablet is not recommended to be used in pregnancy as it may affect your foetus. Consult your doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    ZEOF-400 Tablet is passed into breast milk. Therefore, it is not recommended to be used while breastfeeding. Consult your doctor before taking it to know all the risks and benefits associated with this medicine.


Avoid taking ZEOF-400 Tablet if you are allergic to it. Seek immediate medical attention if you notice any allergic reactions like redness, swelling (anywhere in your body), hives (itchy, painful eruptions that sting), breathing difficulty etc.,

Tendinitis or tendon rupture

ZEOF-400 Tablet can cause muscle damage especially in old age. Do not use ZEOF-400 Tablet if you have tendonitis (swelling of fibres that attach bone with muscles) or tendon rupture (a partial or complete tear of the tendon- the tissue that connects muscle to bone).

Myasthenia gravis

Myasthenia gravis is a skeletal muscle weakness condition characterized by severe weakness of any of the muscles under your voluntary control, including the arms and legs. ZEOF-400 Tablet should be avoided if you have myasthenia gravis since it may get worsen.
Warnings for special population


ZEOF-400 Tablet is not recommended to be used in pregnancy as it may affect your foetus. Consult your doctor before taking this medicine.


ZEOF-400 Tablet is passed into breast milk. Therefore, it is not recommended to be used while breastfeeding. Consult your doctor before taking it to know all the risks and benefits associated with this medicine.
General warnings

Muscle damage

ZEOF-400 Tablet can cause muscle damage usually on the tendons that surround the ankle. Inform your doctor if you feel pain, numbness, or tingling sensations in your muscles.

Antibiotic resistance

Finish your entire course of treatment with ZEOF-400 Tablet, even if the condition gets better to avoid antibiotic resistance (the bacteria may become resistant to antibiotics). If you still feel unwell after completing your antibiotic course, make an appointment to consult your doctor.

Driving or operating machinery

ZEOF-400 Tablet may cause dizziness or sleepiness and interfere with eyesight. Hence, do not drive vehicles or operate machines after taking this medicine.


ZEOF-400 Tablet may make you more sensitive to sunlight or tanning lights. Use sunscreens or wear protective clothing to avoid adverse reactions before stepping outside.


ZEOF-400 Tablet can cause diarrhoea because it may also kill the helpful bacteria in your stomach or intestine. Inform your doctor immediately if you experience severe diarrhoea that is watery or bloody.


If you are taking an antacid containing aluminium and magnesium salts for indigestion, it can increase the time it takes for ZEOF-400 Tablet to act on your body. Because of this, it is recommended to take this antibiotic at least 1 hour before or 2 hours after taking antacids.

Missed Dose

Do not skip any dose of ZEOF-400 Tablet. If you forget to take a dose, take it as soon as you remember. If your next dose time is near, skip the missed dose and take your next scheduled dose. Do not double your dose to make up for the missed one.


Never take more than the prescribed dose. Seek emergency medical attention if you suspect that you might have taken an overdose of ZEOF-400 Tablet.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol




Avoid intake of alcohol while on treatment with ZEOF-400 Tablet. It may lead to increased drowsiness and dizziness.
Interaction with Medicine


Ethinyl Estradiol




Disease interactions

Central nervous system disorders

Take ZEOF-400 Tablet with caution if you have nerve problems, seizures, depression, and psychotic (mental and emotional) disorders as it can worsen these conditions. Inform your doctor immediately if these reactions occur.


ZEOF-400 Tablet is used with extreme caution if you have gastrointestinal (stomach and intestines) diseases, particularly colitis (swelling of the inner lining of the colon), as it may worsen your condition.

QT Prolongation

ZEOF-400 Tablet may cause heart rhythm problems called prolonged QT intervals (an electrical heartbeat disturbance) if you are taking heart medications. It may result in fast, rapid, and irregular heartbeats.

Kidney impairment

ZEOF-400 Tablet should be taken with caution if you have kidney problems as a damaged kidney may lead to accumulation of this medicine and increase the risk of side effects. Your doctor may adjust the dose of this medicine as needed based on your condition.
Food interactions
Avoid consuming multivitamins with minerals while taking ZEOF-400 Tablet. If needed it is suggested to take this medicine before 2 to 4 hours or after 4 to 6 hours of taking multivitamins with minerals.
Lab interactions
Information not available.
Take ZEOF-400 Tablet as instructed by your doctor. Do not crush, break or chew the tablet. ZEOF-400 Tablet is given for a short period. Hence, it is important to complete the whole treatment for maximum benefits. Avoid consuming dairy products and drinking alcohol while taking ZEOF-400 Tablet as it reduces the efficiency of this medicine. Check the expiry date before using ZEOF-400 Tablet. Throw the unused medicine safely after the expiry date. Keep it away from children and pets. Consult your doctor if your condition is not improving or getting worse after taking a few doses of ZEOF-400 Tablet.

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
ZEOF-400 Tablet works by stopping the action of a bacterial enzyme called DNA-gyrase. This prevents the bacterial cells from dividing and repairing, thereby killing them.
Legal Status







Fluoroquinolones, Antibiotics


Schedule H

Drugs, H., 2021. Ofloxacin: Medlineplus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 6 January 2021].


Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 6 January 2021].


Pubchem.ncbi.nlm.nih.gov. 2021. Ofloxacin. [online] Available at: < [Accessed 12 October 2021].

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Information on this page was last updated on 29 Oct 2021


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