DELIVERY LOCATION
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DELIVERY LOCATION
560076
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  3. Xplatin 50 MG Injection

Xplatin 50 MG Injection

Manufacturer
Vhb Life Sciences Inc
Composition
Oxaliplatin
Prescription
Required

Description

Xplatin 50 MG Injection is an anticancer agent which is used in the treatment of cancer of the large intestine. It should be used under the supervision of a qualified physician. Close monitoring of kidney function and blood cell count are necessary while receiving this medication.

Uses of Xplatin 50 MG Injection

What is it prescribed for?

  • Colorectal Cancer

    Xplatin 50 MG Injection is used in the treatment of cancer that affects the large intestine of the digestive system.

Side effects

Major & minor side effects for Xplatin 50 MG Injection

  • Burning or tingling sensation of hands and feetsevere
  • Coughsevere
  • Fever and chillssevere
  • Low WBC and Platelet countsevere
  • Mouth ulcerssevere
  • Loss of appetitesevere
  • Skin rashsevere
  • Nausea and Vomitingsevere
  • Swelling of eyelids, face, lipssevere
  • Acid or sour stomach
  • Sneezing
  • Stomach discomfort and pain
  • Running Nose
  • Change in taste
  • Hair loss
SEVERE
Contact your doctor immediately if any of these symptoms are experienced on a regular basis.
RARE
Observed in a small fraction of population.
This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Highlights

Commonly asked questions for Xplatin 50 MG Injection

Onset of action

The peak effect of this medicine can be observed in 2 hours after intravenous injection.

Duration of effect

The effect of this medicine lasts for an average duration of 30 to 45 days.

Safe with alcohol?

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Is it habit forming?

No habit forming tendencies were reported.

Usage in pregnancy?

This medicine is not recommended for pregnant women.

Usage while breast-feeding?

This medicine is not recommended in breastfeeding women.

Substitutes

List of substitutes for Xplatin 50 MG Injection

Below is the list of medicines, which have the same composition, strength and form as Xplatin 50 MG Injection, and hence can be used as its substitute.
Neoxal 50 MG Injection
Rpg Life Sciences Ltd.
Oxa 50 MG Injection
Emcure Pharmaceuticals Ltd.
Oxichemo 50 MG Injection
Lupin Ltd.
Oxitoz 50 MG Injection
Intas Pharmaceuticals Ltd.
Oxitrust 50 MG Injection
Panacea Biotec Ltd.

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When not to use?

Contraindications of Xplatin 50 MG Injection

  • Allergy

    Not recommended in patients with known allergy to Xplatin 50 MG Injection or other platinum-containing compounds.

  • Severe myelosuppression

    Not recommended in patients with low white blood cell and platelet count.

Dosage

  • Missed Dose

    It is advised not to miss any dose. If you missed any dose, you should contact your doctor immediately.

  • Overdose

    Seek emergency medical treatment or contact the doctor in case of an overdose.

Interactions

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

  • Description

    - Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Instructions

    - Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Medicine

Disease interactions

  • Arrhythmias

    severe
    This medicine should be used with caution in patients with heart diseases due to the increase in the risk of irregular heart rhythm. Monitor the potassium levels, which may exacerbate the condition. Any symptoms of heart palpitation should be reported to the doctor.

  • Lung injury

    severe
    This medicine may cause rare but fatal lung injury. Inform the doctor if you have any lung disease. Any symptoms of difficulty in breathing, non-productive cough should be reported to the doctor. Discontinue the treatment until the exact cause is identified.

Food interactions

  • Information not available.

Lab interactions

  • Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.

General Instructions

This medicine is given in multiple cycles. It is important to receive the every scheduled dose and make a note of next scheduled dose. Close monitoring of blood cells counts and kidney function.

Warnings

Warnings for special population

  • Pregnancy

    - This medicine is not recommended for pregnant women.

  • Breast-feeding

    - This medicine is not recommended in breastfeeding women.

General warnings

  • Impaired kidney function

    - This medicine may cause severe kidney injury. The risk may increase if taken with aminoglycoside antibiotics. Close monitoring of serum creatinine, urea, and sodium levels is necessary.

  • Hearing impairment

    - This medicine may cause the hearing problem which is more common in children. Audiometric testing should be performed before initiating the treatment and also before every dose. Any symptoms of the hearing problem should be reported to the doctor.

  • Allergy

    - This medicine may cause serious skin reactions. Discontinue the treatment if any symptoms of allergy appear and do not restart.

  • Blood cell count

    - This medicine may lower the white blood cells and platelets. Close monitoring of blood cell count is necessary. Do not start the treatment if the cell count is low.

  • Infections

    - The chances of occurring infections are more in patients receiving this medicine. Hold the chemotherapy and start with the broad-spectrum antibiotics if there are any signs and symptoms of fever. Close monitoring of the body temperature and the blood cell count is necessary.

  • Lung toxicity

    - This medicine may cause rare but fatal lung injury. Inform the doctor if you have any lung disease. Any symptoms of difficulty in breathing, non-productive cough should be reported to the doctor. Discontinue the treatment until the exact cause is identified.

  • Impaired liver function

    - This medicine may cause liver injury. The baseline of liver enzymes should be obtained before initiating the therapy. Any signs of elevation in the liver enzymes should be informed to the doctor. Discontinue the treatment until the levels reach to normal.

  • Neuropathy

    - This medicine may cause severe nerve damage which may develop within hours of adminstration and resolves within 14 days or may persist for more than 14 days. Any symptoms of tingling or burning sensation of hands and feet should be reported to the doctor.

Other details

  • Usage does not depend on food timings
  • To be taken as instructed by doctor
  • May cause sleepiness

How it works

It works by stopping the growth of cancer cells by inhibiting the DNA synthesis.

Legal Status

Approved
Approved
Approved
Approved

Classification

Category
Alkylating agents
Schedule
Schedule H

References

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Information on this page was last updated on 16 Nov 2017

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Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.