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Tykerb 250 mg Tablet
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Tykerb 250 mg Tablet

Manufactured byGLAXOSMITHKLINE PHARMACEUTICALS LTD
ContainsLapatinib
Description
Tykerb 250 mg Tablet is an anticancer medicine used in the treatment of breast cancer. Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. This medicine helps in controlling abnormal cell growth by stopping the multiplication of cancer cells, thus causing them to die. This medicine may be given in combination with other medicines as a part of your chemotherapy (the use of medicines to treat cancer). Tykerb 250 mg Tablet can cause side effects like fatigue, nausea, vomiting, diarrhoea, and loss of appetite. Most of them are temporary and resolve with time. Consult your doctor if these side effects are bothering you for a long time or getting worse. Avoid driving vehicles and operating machines after taking this medicine, as it can make you feel dizzy. Tykerb 250 mg Tablet should be taken before a meal or as instructed by your doctor. Your dose and duration of treatment will be decided by your doctor based on your clinical condition. Take it at the same time daily for the ease of remembering. Avoid taking more than the recommended dose as it may increase the risk of serious side effects. Take this medicine for the recommended duration. Avoid the discontinuation of this medicine without consulting your doctor, as your condition may become worse. Tykerb 250 mg Tablet is not recommended if you are allergic to it. Inform your doctor about your current medicines and medical conditions before taking this medicine. This will help your doctor adjust the dose to avoid side effects. If you are pregnant or breastfeeding, consult your doctor before taking this medicine.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Tykerb 250 mg Tablet

  • Decreased appetite or loss of appetite
  • Difficulty in breathing
  • Stomach pain
  • Back pain or Joint pain
  • Clay colored stools
  • Fast or irregular heartbeat
  • Yellow eyes or skin
  • Dark urine
  • Headache
  • Severe diarrhoea
  • Fatigue
  • Skin rash
  • Nausea or vomiting

Uses of Tykerb 250 mg Tablet

What is it prescribed for?

  • Breast cancer
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for Tykerb 250 mg Tablet to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The time duration for which Tykerb 250 mg Tablet remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Tykerb 250 mg Tablet.
  • Can this medicine be taken during pregnancy?
    Tykerb 250 mg Tablet is unsafe for use during pregnancy as it may cause harm to the developing foetus. Hence consult your doctor if you are pregnant.
  • Can this medicine be taken while breast-feeding?
    Due to the lack of safety information, Tykerb 250 mg Tablet is not recommended for use while breastfeeding.

Allergy

Avoid taking Tykerb 250 mg Tablet if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.
Warnings for special population

Pregnancy

Tykerb 250 mg Tablet is unsafe for use during pregnancy as it may cause harm to the developing foetus. Hence consult your doctor if you are pregnant.

Breast-feeding

Due to the lack of safety information, Tykerb 250 mg Tablet is not recommended for use while breastfeeding.
General warnings

Blood cell count

Tykerb 250 mg Tablet may lower the white blood cell and platelet (blood clot-forming cells) counts, which can make you more prone to infection and bleeding. Your doctor may closely monitor your complete blood cell counts during treatment with this medicine.

Driving or operating machines

Tykerb 250 mg Tablet may cause dizziness in some cases. Hence avoid performing activities that require mental alertness, such as driving vehicles or operating machines, if you feel dizzy during treatment with this medicine.

Severe cutaneous adverse reactions

Tykerb 250 mg Tablet should be used with caution as it may cause severe cutaneous (skin) adverse reactions in some cases. Hence limit your exposure to sunlight and wear sunscreen and protective clothing, as exposure to sunlight may aggravate such conditions.

Severe diarrhoea

Tykerb 250 mg Tablet may cause severe diarrhoea in some cases. Consult your doctor if it persists or worsens.

Missed Dose

Take the missed dose of Tykerb 250 mg Tablet as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Never take more than the prescribed dose. Seek emergency medical treatment in case of an overdose of Tykerb 250 mg Tablet.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Clonazepam

Omeprazole

Teriflunomide

Digoxin

Cisapride

Disease interactions

Cardiac Dysfunction

QT prolongation is a condition in which your heart muscles take a longer time to recharge between a heartbeat. Tykerb 250 mg Tablet may cause QT prolongation and should be used with extreme caution if you have heart problems.

Lung impairment

Tykerb 250 mg Tablet should be used with extreme caution if you have lung problems as this medicine may cause pulmonary toxicity (damage to the lungs).

Liver impairment

Tykerb 250 mg Tablet should be used with extreme caution if you have liver problems as this medicine may cause liver toxicity. Your doctor may recommend dose adjustments based on your clinical condition.

Kidney impairment

Tykerb 250 mg Tablet should be used with caution if you have kidney problems. Follow all the instructions given by your doctor.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Tykerb 250 mg Tablet as instructed by your doctor. Do not take more or less than the prescribed dose. Drink plenty of water with it to avoid stomach irritation. Do not stop the use of this medicine without consulting your doctor, as it may worsen your condition. Tykerb 250 mg Tablet may cause severe diarrhoea. Consult your doctor if it persists or worsens. Avoid driving vehicles or operating machines if you feel dizzy after taking Tykerb 250 mg Tablet. Throw away unused medicine safely after the expiry date. Keep it away from children and pets.
Miscelleneous

To be taken on an empty stomach

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Tykerb 250 mg Tablet helps in controlling abnormal cell growth by stopping the multiplication of cancer cells, thus causing them to die.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Antineoplastics, HER2 inhibitors, EGFR inhibitors

Schedule

Schedule H

Drugs, H., 2022. Lapatinib: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: [Accessed 1 April 2022].

https://medlineplus.gov/druginfo/meds/a607055.html

Pubchem.ncbi.nlm.nih.gov. 2022. Lapatinib. [online] Available at: [Accessed 1 April 2022].

https://pubchem.ncbi.nlm.nih.gov/compound/Lapatinib

Medicines.org.uk. 2022. [online] Available at: [Accessed 1 April 2022].

https://www.medicines.org.uk/emc/files/pil.6292.pdf

Accessdata.fda.gov. 2022. [online] Available at: [Accessed 1 April 2022].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/022059s007lbl.pdf

2022. [online] Available at: [Accessed 1 April 2022].

https://www.dana-farber.org/uploadedFiles/Pages/Health_Library/Articles/Lapatinib-Tykerb.pdf

Ema.europa.eu. 2022. [online] Available at: < [Accessed 1 April 2022].

https://www.ema.europa.eu/en/documents/product-information/tyverb-epar-product-information_en.pdf>
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Information on this page was last updated on 20 Sep 2022

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