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Tablura 80 Tablet
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Tablura 80 Tablet

Manufactured byCIPLA LTD
ContainsLurasidone
Description
Tablura 80 Tablet is an antipsychotic medicine (medicines used to treat mental conditions). It is used for the treatment of schizophrenia (a mental condition in which a person is unable to differentiate between the real-world and imaginary world) and episodes of depression in bipolar disorder (a mental condition with extreme mood swings with an emotional high or low). It works by blocking the release of certain chemicals that cause such conditions. Tablura 80 Tablet shows common side effects such as stiffness in muscles, weight gain, nausea, vomiting, running nose, sleep problems, and restlessness. If these symptoms persist or worsen, consult your doctor for further assistance. Avoid driving vehicles or operating heavy machines as it can cause drowsiness. Tablura 80 Tablet should be taken with food. Do not chew, crush, or break the tablet. Swallow it as a whole with plenty of water. Take the medicine at the same time daily for ease of remembering. Avoid consuming grapefruit juice while taking this medicine, as it can increase the concentration of Tablura 80 Tablet in your bloodstream leading to increased side effects. Do not discontinue the medicine without consulting your doctor, as it can worsen your condition. Tablura 80 Tablet is not recommended if you are allergic to it. Take this medicine with caution if you have heart conditions, depression, abnormally low blood pressure, increased fat levels, high blood sugar levels, or low white blood cell count. Inform your doctor before taking the medicine if you have breast cancer, high prolactin levels, seizures (a brain condition due to abnormal electrical activity in the brain leading to jerking movements, fear, anxiety, and loss of consciousness), or liver/kidney conditions. Tablura 80 Tablet is not recommended if you have neuroleptic malignant syndrome (NMS), characterised by high body temperature, muscle rigidity, altered mental status, irregular blood pressure, irregular heart rhythm, etc., as it can worsen your condition. Tablura 80 Tablet should only be taken during pregnancy and breastfeeding after consulting your doctor. It is not recommended for use in children below 10 years of age to treat bipolar disorder and below 13 years of age to treat schizophrenia.
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Side effectsConcernsUsageRelated products

Substitutes

List of substitutes for Tablura 80 Tablet

Unisidon 80 Tablet
Torrent Pharmaceuticals Ltd.

Side effects

Major & minor side effects for Tablura 80 Tablet

  • Difficulty with swallowing
  • Slurred speech
  • Stiffness of arms and legs
  • Blurred vision
  • Chest pain or discomfort
  • Headache
  • Unusual tiredness or weakness
  • Sleep disturbances
  • Anxiety
  • Dry mouth
  • Drowsiness
  • Weight gain

Uses of Tablura 80 Tablet

What is it prescribed for?

  • Schizophrenia
  • Bipolar disorder
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The time taken by Tablura 80 Tablet to show its effect is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which Tablura 80 Tablet remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with Tablura 80 Tablet due to the increased risk of side effects such as dizziness, difficulty in concentration, impaired judgment, etc.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Tablura 80 Tablet.
  • Can this medicine be taken during pregnancy?
    Tablura 80 Tablet should only be taken during pregnancy upon your doctor's recommendation.
  • Can this medicine be taken while breast-feeding?
    Consult your doctor before taking Tablura 80 Tablet if you are breastfeeding.

Allergy

Avoid taking Tablura 80 Tablet if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Strong CYP3A4 inhibitors

CYP3A4 is an enzyme in the body that is responsible for the breakdown of toxins and medicines so that they can get removed from the body. CYP3A4 inhibitors are a class of medicines that can inhibit the activity of the CYP3A4 enzyme. Tablura 80 Tablet is not recommended for use if you are receiving treatment with strong CYP3A4 inhibitors such as Ketoconazole, Clarithromycin, Voriconazole, etc., due to the increased risk of serious side effects.

Strong CYP3A4 Inducers

CYP3A4 is an enzyme in the body that is responsible for the breakdown of toxins and medicines so that they can get removed from the body. CYP3A4 inducers are medicine that may increase the activity of the CYP3A4 enzyme. Tablura 80 Tablet is not recommended for use if you are receiving treatment with strong CYP3A4 inducers such as Rifampin, Phenytoin, Carbamazepine, etc., as it may worsen your condition.
Warnings for special population

Pregnancy

Tablura 80 Tablet should only be taken during pregnancy upon your doctor's recommendation.

Breast-feeding

Consult your doctor before taking Tablura 80 Tablet if you are breastfeeding.
General warnings

Suicidal ideation

Tablura 80 Tablet should be used with caution as it may increase the risk of suicidal thoughts and behaviour. Follow all the instructions given by your doctor.

Breast cancer

Tablura 80 Tablet should be used with caution as it may cause an increase in prolactin (a hormone that causes breast tissue development and milk production after delivery) levels in the body and increase the risk of breast cancer. Follow all the instructions given by your doctor.

Liver or kidney conditions

Tablura 80 Tablet should be used with caution if you have liver or kidney conditions. Your doctor may recommend dose adjustments based on your clinical condition. Follow all the instructions given by your doctor.

Heart condition

QT prolongation is a condition in which your heart muscles take a longer time to recharge between a heartbeat. Tablura 80 Tablet should be used with caution as it may cause QT prolongation. Inform your doctor if you have heart conditions before taking this medicine.

Hypotension

Tablura 80 Tablet should be used with caution as it may cause hypotension (abnormally low blood pressure). Follow all the instructions given by your doctor.

High cholesterol level

Tablura 80 Tablet may cause an alteration in lipid (fats) levels and should be used with caution if you have increased fat levels in the blood. Follow all the instructions given by your doctor.

Low white blood cell count

Tablura 80 Tablet should be used with caution as it may cause low white blood cell count. Your doctor may suggest blood tests to monitor your white blood cell count while you are taking this medicine.

Use in children

Tablura 80 Tablet is not recommended for use in children below ten years of age to treat bipolar disorder and below 13 years of age to treat schizophrenia.

Tardive dyskinesia

Tardive dyskinesia is a movement disorder characterised by involuntary and abnormal movements of the jaw, lips, tongue, trunk, and extremities. Tablura 80 Tablet should be used with extreme caution as it may cause tardive dyskinesia.

Driving or operating machines

Tablura 80 Tablet may cause drowsiness. Hence avoid driving vehicles or operating machines if you feel drowsy after taking the medicine.

Missed Dose

Do not miss the dose of Tablura 80 Tablet. Take the missed dose as soon as possible. Skip the missed dose if it is already time for your next scheduled dose. Do not use extra medicine to make up for the missed dose.

Overdose

Do not take more than the recommended dose of Tablura 80 Tablet. Seek emergency medical treatment in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with Tablura 80 Tablet due to the increased risk of side effects such as dizziness, difficulty in concentration, impaired judgment, etc.
Interaction with Medicine

Atazanavir

Bupropion

Fluconazole

Codeine

Disease interactions

Seizures

Tablura 80 Tablet should be used with caution if you have a history of seizures (a brain condition due to abnormal electrical activity in the body leading to jerking movements and loss of consciousness), as this medicine may trigger a seizure attack. Follow all the instructions given by your doctor.

Diabetes

Tablura 80 Tablet should be used with caution if you have diabetes (abnormally high blood sugar level). Follow all the instructions given by your doctor.

Dementia- related psychosis

Elderly with dementia-related psychosis (memory loss along with hallucinations) should avoid taking Tablura 80 Tablet as it can increase the risk of death due to heart failure (the heart is unable to pump enough blood throughout the body) or infections.

Neuroleptic Malignant Syndrome (NMS)

Neuroleptic malignant syndrome (NMS) is a rare but life-threatening reaction that can occur in response to the use of antipsychotic medication. It is characterised by high body temperature, muscle rigidity, altered mental status, irregular blood pressure, irregular heart rhythm, etc. Tablura 80 Tablet is not recommended if you have neuroleptic malignant syndrome (NMS) as it can worsen your condition.
Food interactions
Consumption of grapefruit juice is not recommended during treatment with Tablura 80 Tablet as it may increase the blood levels and effects of this medicine, thus increasing the risk of undesired effects.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Tablura 80 Tablet with food. Avoid taking more or less than the recommended dose. Take this tablet at the same time daily for ease of remembering and to maintain a constant level of medicine in the body. Do not chew, crush, and break the tablet. Swallow it whole with a glass of water. Drink an adequate amount of water to avoid dehydration during treatment with this medicine. Do not discontinue the medicine without consulting with your doctor, as your condition may become worse. Avoid the consumption of alcohol or grapefruit juice while taking Tablura 80 Tablet due to the increased risk of side effects. Consult your doctor if you experience mood changes or develop suicidal thoughts while taking this medicine. Tablura 80 Tablet may cause weight gain. Hence it is recommended to monitor your body weight during treatment with this medicine.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

Causes sleepiness

How it works
Tablura 80 Tablet works by blocking the release of certain chemicals responsible for mental conditions such as schizophrenia and bipolar disorder.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Atypical antipsychotics

Schedule

Schedule H

Nice.org.uk. 2022. Key points from the evidence | Schizophrenia: lurasidone | Advice | NICE. [online] Available at: [Accessed 12 July 2022].

https://www.nice.org.uk/advice/esnm48/chapter/key-points-from-the-evidence#:~:text=The%20recommended%20starting%20dose%20is,daily%20together%20with%20a%20meal.

Stewart, M., 2022. Lurasidone (Latuda) | Medicine. [online] Patient.info. Available at: o/medicine/lurasidone-latuda [Accessed 12 July 2022].

https://patient.inf

Azhar, Y. and Shaban, K., 2022. Lurasidone. [online] Ncbi.nlm.nih.gov. Available at: [Accessed 12 July 2022].

https://www.ncbi.nlm.nih.gov/books/NBK541057/#:~:text=Lurasidone%20takes%201%20to%203,and%20alpha%2D1%20acid%20glycoprotein.

Cruz, M., 2022. Lurasidone HCl (Latuda), an Oral, Once-Daily Atypical Antipsychotic Agent for the Treatment of Patients with Schizophrenia. [online] PubMed Central (PMC). Available at: [Accessed 12 July 2022].

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171824/#:~:text=PREGNANCY%20AND%20BREAST%2DFEEDING,have%20been%20conducted%20during%20pregnancy.
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Information on this page was last updated on 24 Aug 2022

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