Skizolev 25 MG Tablet

Manufactured byAlkem Laboratories Ltd.
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Description

Skizolev 25 MG Tablet belongs to the class of antipsychotic medicines. However, it is primarily used for its gut motility properties i.e to improve food movement and treats disorders of the stomach and intestines.

Side effects

Major & minor side effects for Skizolev 25 MG Tablet

  • Drowsiness
  • Breast tenderness
  • Irregular menstrual periods
  • Gynacomastia
  • Cosntipation
  • Abdominal pain and cramps
  • Weight gain
  • Sleeplessness
  • Unusual tiredness and weakness
  • Increased salivation
  • Decrease in libido
  • Fever
  • Excessive sweating
  • Change in heart rate

Uses of Skizolev 25 MG Tablet

What is it prescribed for?

  • Gastroesophagal Reflux Disease
  • Irritable bowel syndrome
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Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed within 1-2 hours of oral administration.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 5-8 hours upon oral administration.
  • Safe with alcohol?
    Avoid or limit the uptake of alcohol while taking this medicine as the risk of adverse effects are increasingly high. Contact your doctor if an excess of drowsiness is experienced.
  • Is it habit forming?
    No habit forming tendencies were reported.
  • Usage in pregnancy?
    Use of this medicine during pregnancy is not recommended unless absolutely necessary. It is advised to use this medicine only when the benefits outweigh the risks involved.
  • Usage while breast-feeding?
    Use of this medicine by breastfeeding women is not recommended. However, if it is absolutely necessary to use this medicine, then breastfeeding should be discontinued. Consult your doctor before using this medicine.

Allergy

This medicine is not recommended for use if you have a known history of allergy to Levosulpiride or any other component present with it.

Epilepsy

This medicine is not recommended for use if you suffer from epilepsy or have a history of convulsions.

Bipolar disorder

This medicine is not recommended for use in patients suffering from bipolar disorder marked by frequent episodes of anxiety, agitation, depression, hallucinations etc.

Pheochromocytoma

This medicine is not recommended for use in patients having a tumor of the adrenal glands that causes a life threatening rise in blood pressure.

Gastrointestinal perforation

This medicine is not recommended for use if you have a condition where the food pipe and the gut is bleeding, obstructed, and perforated.

Breast cancer

This medicine is not recommended for use if you have been diagnosed with breast cancer (malignant mastopathy).
Warnings for special population

Pregnancy

Use of this medicine during pregnancy is not recommended unless absolutely necessary. It is advised to use this medicine only when the benefits outweigh the risks involved.

Breast-feeding

Use of this medicine by breastfeeding women is not recommended. However, if it is absolutely necessary to use this medicine, then breastfeeding should be discontinued. Consult your doctor before using this medicine.
General warnings

Heart disease

This medicine should be used with caution in patients having a history of stroke, blood clotting disorders or other ailments of the heart and blood vessels.

Diabetes

This medicine should be used with caution in patients who are suffering from diabetes or are exposed to the risk factors.

Hypokalemia

This medicine should be used with caution in patients having low potassium levels in the body. It is recommended to initiate treatment with Skizolev 25 MG Tablet only after the potassium deficit is corrected.

Breast cancer

This medicine is not recommended for use if the patient is suspected to have breast cancer associated with abnormally high levels of prolactin in the body.

Drowsiness

This medicine is known to cause moderate to severe drowsiness and may the ability to perform tasks that require a high level of mental alertness. It is advised to refrain from driving or operating any heavy machinery after consuming this medicine.

Leukopenia

This medicine is not recommended for use in patients who have a decreased white blood cell count characterized by frequent infections, fever with chills, sore throat, and mouth ulcers.

Use in elderly

This medicine should be used with caution in the elderly as the risk of side effects are increasingly high. Appropriate dose adjustments should be made based on the response of the patients.

Menstrual abnormalities

Use of this medicine has been associated with abnormalities in menstrual period. Contact your doctor if the regular periods are excessively delayed.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for the next scheduled dose, then the missed dose can be skipped.

Overdose

Contact a doctor if an overdose with Skizolev 25 MG Tablet is suspected. Symptoms of an overdose may include excessive drowsiness, fall in blood pressure, agitation, coma etc.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Consumption of alcohol while taking this medicine can cause CNS depression characterized by confusion, lack of focus, anxiety, drowsiness etc.

Instructions

Avoid or limit the uptake of alcohol while taking this medicine as the risk of adverse effects are increasingly high. Contact your doctor if an excess of drowsiness is experienced.
Interaction with Medicine

Diltiazem

Pregabalin

Sucralfate

Tramadol

Aluminium Hydroxide/Magnesium Hydroxide

Ipratropium

Disease interactions

Heart Disease

This medicine should be used with caution in patients suffering from a disease of the heart and blood vessels. You may require an adjusted dose and safety monitoring to safely use this medicine.

Gastro-intestinal bleeding

This medicine should be used with extreme caution in patients suffering from perforation and bleeding of the stomach and the intestine. Report any instance of fever with chills, nausea, vomiting, presence of blood in stool to the doctor.

Prolactin imbalance

This medicine should not be used in patients having an abnormal level of the hormone prolactin. Breast cancer due to a high level of prolactin should be ruled out before treatment with this medicine is initiated.

Neuroleptic Malignant Syndrome (NMS)

Use of this medicine is not recommended if the patient suffers from Neuroleptic malignant syndrome. Introduction or reintroduction of this medicine should be done with caution in patients having a known history of this syndrome.

Asthma

This medicine should be used with caution if you have asthma. Report any instances of difficulty in breathing, wheezing, chest pain etc to the doctor immediately.
Food interactions
Information not available.
Lab interactions

Prolactin test

Report the use of this medicine before undergoing a laboratory test to determine the levels of the hormone prolactin in the body. This medicine can interfere with the test and yield false positive results.
Take Skizolev 25 MG Tablet as instructed by the doctor. This medicine should be taken at least half an hour before food. Do not take this medicine in larger or smaller quantities than recommended. It is advised to take plenty of water while taking this medicine.
Miscelleneous

To be taken before food

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by inhibiting the action of certain specific neurotransmitters in the brain and specific regions of the stomach and the intestine.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Atypical antipsychotics, GI stimulants

Schedule

Schedule H

Levosulpiride | C15H23N3O4S - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 12 May 2017]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/688272#section=Top

Sulpiride - DrugBank [Internet]. Drugbank.ca. 2017 [cited 12 May 2017]. Available from:

https://www.drugbank.ca/drugs/DB00391

[Internet]. Medind.nic.in. 2017 [cited 16 November 2017]. Available from:

http://medind.nic.in/daa/t07/i2/daat07i2p144.pdf

[Internet]. Mri.cts-mrp.eu. 2017 [cited 16 November 2017]. Available from:

http://mri.cts-mrp.eu/download/IT_H_0367_001_FinalPL.pdf
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