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Lesuride MPS Tablet

Manufactured bySun Pharma Laboratories Ltd.
Description

Lesuride MPS Tablet belongs to the class of antipsychotic medicines. However, it is primarily used for its action on the gastrointestinal tract i.e to improve food movement and treats disorders of the stomach and intestines. It may also be used for the treatment of schizophrenia and depression.

Side effects

Major & minor side effects for Lesuride MPS Tablet

  • Drowsiness
  • Breast tenderness
  • Irregular menstrual periods
  • Breast enlargement in men
  • Cosntipation
  • Abdominal pain and cramps
  • Weight gain
  • Sleeplessness
  • Unusual tiredness and weakness
  • Increased salivation
  • Decrease in libido
  • Fever
  • Excessive sweating
  • Change in heart rate
  • Tremor (Shaking and trembling of arms and feet)
  • Muscle rigidity
  • Decreased blood pressure

Uses of Lesuride MPS Tablet

What is it prescribed for?

  • Gastroesophagal Reflux Disease (heartburn)
  • Irritable bowel syndrome (a condition of the digestive system)
  • Schizophrenia
  • Depression
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of severe adverse effects. These side effects may include confusion, dizziness, nausea, vomiting, weakness, fainting, etc. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol while taking this medicine.
  • Is this a habit forming medicine?
    No habit forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use if you have a known history of allergy to levosulpiride or any other inactive ingredients present in the formulation.

Epilepsy

This medicine is not recommended for use in patients suffering from epilepsy due to the increased risk of worsening of the patient's condition.

Bipolar disorder

This medicine is not recommended for use in patients suffering from bipolar disorder, marked by frequent episodes of anxiety, agitation, depression, hallucinations etc., due to the increased risk of worsening of the patient's condition.

Pheochromocytoma

This medicine is not recommended for use in patients having a tumor of the adrenal glands that causes a life threatening rise in blood pressure.

Gastrointestinal perforation

This medicine is not recommended for use in patients suffering from perforation or obstruction of the gastrointestinal tract since it may worsen the patient's condition.

Breast cancer

This medicine is not recommended for use in patients suffering from breast cancer (malignant mastopathy) due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Diabetes

This medicine should be used with caution in patients with diabetes mellitus because it may alter the blood glucose levels in such patients. Close monitoring of blood glucose levels is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Hypokalemia

This medicine should be used with caution in patients having low potassium levels in the body. It is recommended to initiate treatment with this medicine only after the potassium deficit is corrected. Close monitoring of potassium levels, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Breast cancer

This medicine is not recommended for use if the patient is suspected to have breast cancer associated with abnormally high levels of prolactin in the body.

Driving or operating machinery

This medicine may cause blurred vision, drowsiness or dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Leukopenia

This medicine is not recommended for use in patients who have a decreased white blood cell count characterized by frequent infections, fever with chills, sore throat, and mouth ulcers.

Use in elderly

This medicine should be used with extreme caution in the elderly population due to the increased risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Menstrual abnormalities

Use of this medicine has been associated with abnormalities in the menstrual cycle. Contact your doctor if the regular periods are excessively delayed. Replacement with a suitable alternative may be necessary in some cases.

QT prolongation

This medicine should be used with extreme caution in patients with a known history of prolonged QT intervals due to the increased risk of worsening of the patient's condition. Report any unusual symptoms to the doctor immediately. Close monitoring of the clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Use in children

This medicine is not recommended for use in children below 18 years of age since the safety and efficacy of use are not clinically established.

Diabetes

This medicine should be used with caution in patients with diabetes mellitus because it may alter the blood glucose levels in such patients. Close monitoring of blood glucose levels is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Hypokalemia

This medicine should be used with caution in patients having low potassium levels in the body. It is recommended to initiate treatment with this medicine only after the potassium deficit is corrected. Close monitoring of potassium levels, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Breast cancer

This medicine is not recommended for use if the patient is suspected to have breast cancer associated with abnormally high levels of prolactin in the body.

Driving or operating machinery

This medicine may cause blurred vision, drowsiness or dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Leukopenia

This medicine is not recommended for use in patients who have a decreased white blood cell count characterized by frequent infections, fever with chills, sore throat, and mouth ulcers.

Use in elderly

This medicine should be used with extreme caution in the elderly population due to the increased risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Menstrual abnormalities

Use of this medicine has been associated with abnormalities in the menstrual cycle. Contact your doctor if the regular periods are excessively delayed. Replacement with a suitable alternative may be necessary in some cases.

QT prolongation

This medicine should be used with extreme caution in patients with a known history of prolonged QT intervals due to the increased risk of worsening of the patient's condition. Report any unusual symptoms to the doctor immediately. Close monitoring of the clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Use in children

This medicine is not recommended for use in children below 18 years of age since the safety and efficacy of use are not clinically established.

Missed Dose

Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of severe adverse effects. These side effects may include confusion, dizziness, nausea, vomiting, weakness, fainting, etc. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol while taking this medicine.
Interaction with Medicine

Diltiazem

Pregabalin

Sucralfate

Tramadol

Aluminium Hydroxide/Magnesium Hydroxide

Ipratropium

Disease interactions

Heart Disease

This medicine should be used with caution in patients suffering from heart diseases due to the increased risk of severe adverse effects. Close monitoring of heart function and vital signs, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Prolactin imbalance

This medicine is not recommended for use in patients having an abnormal level of the hormone prolactin. Breast cancer due to a high level of prolactin should be ruled out before treatment with this medicine is initiated.

Neuroleptic Malignant Syndrome (NMS)

This medicine is not recommended for use in patients with a history of Neuroleptic malignant syndrome due to the increased risk of recurrent symptoms. If the medicine is used, the patient should be monitored closely for any unusual symptoms such as extreme fever, muscle rigidity, irregular heart rate, and blood pressure, excessive sweating, etc. Replacement with a suitable alternative should be considered based on the clinical condition of the patient.

Asthma

This medicine should be used with caution in patients with a history of asthma due to the increased risk of severe adverse effects. Report any symptoms such as difficulty in breathing, wheezing, chest pain, etc. to the doctor immediately. Close monitoring of the clinical conditions, appropriate dose adjustments, or replacement with a suitable alternative may be necessary in some cases.
Food interactions
Information not available.
Lab interactions

Prolactin test

Report the use of this medicine before undergoing a laboratory test to determine the levels of the hormone prolactin in the body. This medicine may interfere with the test and yield false-positive results.
Take this medicine exactly advised by your doctor. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable effects. Do not stop taking this medicine before completion of the course/without consulting your doctor.
Miscelleneous

To be taken before food

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by inhibiting the action of certain specific neurotransmitters in the brain and specific regions of the stomach and the intestine.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Atypical antipsychotics, GI stimulants

Schedule

Schedule H

Levosulpiride | C15H23N3O4S - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 12 May 2017]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/688272#section=Top

Sulpiride - DrugBank [Internet]. Drugbank.ca. 2017 [cited 12 May 2017]. Available from:

https://www.drugbank.ca/drugs/DB00391

[Internet]. Medind.nic.in. 2017 [cited 16 November 2017]. Available from:

http://medind.nic.in/daa/t07/i2/daat07i2p144.pdf
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Information on this page was last updated on 9 Apr 2020

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