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Seretide 50/250 Accuhaler

Manufactured byGlaxosmithkline Pharmaceuticals Ltd.
ContainsFluticasone propionate (250 mcg) + Salmeterol (50 mcg)
Description
Seretide 50/250 Accuhaler is a combination of Fluticasone Propionate and Salmeterol. This medicine is used to relieve symptoms such as wheezing, shortness of breath, chest tightness, breathing difficulty, coughing, etc. caused by asthma (a condition that causes narrowing of the airways) and chronic obstructive pulmonary disease (lung conditions in which the airflow is blocked, leading to breathing difficulty). It works by relaxing and widening the muscles in your airways. Seretide 50/250 Accuhaler may cause some side effects like headache, throat irritation, stuffy nose, and hoarseness of voice. Inform your doctor if these side effects remain for a long time or become severe. Avoid using it if you are allergic to it. Seretide 50/250 Accuhaler should be used in the dose and duration prescribed by your doctor. For the ease of remembering, use it around the same time every day. Even if you see an improvement in your condition, do not stop using it. If you discontinue this medicine early, your symptoms may reoccur. It should not be used to relieve sudden asthma attacks. Seretide 50/250 Accuhaler may not be suitable for all people. It is not recommended for use in children below 12 years of age. Inform your doctor if you have liver or heart problems, diabetes, active infections, or other medical conditions. Consult your doctor if you are pregnant, planning a pregnancy, or are breastfeeding.

Side effects

Major & minor side effects for Seretide 50/250 Accuhaler

  • Blurred vision
  • Cough
  • Fever
  • Nausea and Vomiting
  • Headache
  • Runny Nose
  • Muscle pain
  • White patches in the mouth or on the tongue
  • Sore throat and hoarseness

Uses of Seretide 50/250 Accuhaler

What is it prescribed for?

  • Asthma
  • Chronic obstructive pulmonary disease
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for Seretide 50/250 Accuhaler to show its effect is not clinically known.
  • How long do the effects of this medicine last?
    The amount of time for which Seretide 50/250 Accuhaler remains active in your body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Seretide 50/250 Accuhaler.
  • Can this medicine be taken during pregnancy?
    Seretide 50/250 Accuhaler is not recommended for use in pregnancy unless necessary. Hence, consult your doctor before using this medicine.
  • Can this medicine be taken while breast-feeding?
    Seretide 50/250 Accuhaler is not recommended for use while breastfeeding unless necessary. Hence, consult your doctor before using this medicine.

Allergy

Avoid using Seretide 50/250 Accuhaler if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (of your face/tongue/throat), breathing difficulty, etc.

Status asthmaticus

Status asthmaticus is a severe form of asthma that is sudden and does not respond to standard treatments. These attacks can last for several minutes or even hours. Seretide 50/250 Accuhaler is not recommended for use if you have status asthmaticus as it is not effective in treating this condition.
Warnings for special population

Pregnancy

Seretide 50/250 Accuhaler is not recommended for use in pregnancy unless necessary. Hence, consult your doctor before using this medicine.

Breast-feeding

Seretide 50/250 Accuhaler is not recommended for use while breastfeeding unless necessary. Hence, consult your doctor before using this medicine.
General warnings

Hypokalaemia

Seretide 50/250 Accuhaler may cause a decrease in blood potassium levels and lead to heart-related complications. Hence this medicine should be used with caution if you have hypokalaemia (low blood potassium levels).

Seizure disorder

Seizure is an abnormal and uncontrolled electrical activity in the brain causing uncontrolled jerking of the body. Seretide 50/250 Accuhaler should be used with caution if you have seizure disorder as it may worsen your condition.

Use in children

Seretide 50/250 Accuhaler is not recommended for use in children less than 12 years of age as the safety and efficacy data are not clinically established.

Missed Dose

If you miss a dose of Seretide 50/250 Accuhaler, administer the missed dose as soon as you remember. If it is time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment in case of an overdose of Seretide 50/250 Accuhaler.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Atazanavir

Amprenavir

Itraconazole

Clarithromycin

Disease interactions

Cardiovascular disorders

Seretide 50/250 Accuhaler should be used with caution if you have problems related to the heart and blood vessels. This medicine may cause an irregular heart rhythm, increased heartbeat, blood pressure changes, etc., leading to further complications.

Hyperadrenocorticism

Hyperadrenocorticism is a condition that occurs due to high levels of cortisol hormone (a chemical substance that helps your body respond to stress, regulate blood sugar, and fight infections) in the body. The symptoms include rapid weight gain, flushed and round face, bruises, and purple stretch marks, muscle weakness, etc. Use of high doses of Seretide 50/250 Accuhaler for prolonged time should be done with caution as it may lead to this condition.

Infections

Seretide 50/250 Accuhaler should be used with caution as it may suppress the infection-fighting ability of your body and increase the risk of infections of the mouth and throat.

Osteoporosis

Osteoporosis is a condition of weak and brittle bones. Seretide 50/250 Accuhaler should be used with caution as it may decrease bone mineral density and weaken your bones.

Hepatic impairment

Seretide 50/250 Accuhaler should be used with caution if you have liver problems as this medicine may not break down completely and accumulate in your body, leading to serious side effects.

Diabetes

Diabetes is a condition of increased blood sugar levels in your body. Seretide 50/250 Accuhaler should be used with caution if you have diabetes as it may worsen your condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Use Seretide 50/250 Accuhaler as prescribed by your doctor. Follow all the instructions given on the information leaflet or the package insert. Do not use in larger or smaller amounts than prescribed. Do not stop the use of this medicine without consulting your doctor as it may worsen your condition. Consult your doctor if you experience any undesirable effects that persist or worsen. Seretide 50/250 Accuhaler is not effective in treating an asthma attack that has already started. Always use a rescue inhaler to treat such symptoms. Consult your doctor to understand which medications to be used on a daily basis and which you should use if you have sudden breathing problems (asthma attacks).
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
Seretide 50/250 Accuhaler is a combination of Fluticasone Propionate and Salmeterol. Fluticasone propionate works by inhibiting the release of certain substances in the body that cause inflammation (swelling, redness, pain, etc.). Salmeterol relaxes and widens the blocked air passages leading to the lungs. This improves the amount of airflow to the lungs and makes breathing easier.
Legal Status

Approved

Approved

Unknown

Approved

Classification

Category

Bronchodilators, Inhaled corticosteroids

Schedule

Schedule H

Medicines.org.uk. 2022. Fixkoh Airmaster 50 microgram/250 microgram/ dose inhalation powder, pre-dispensed - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 5 January 2022].

https://www.medicines.org.uk/emc/product/12080/smpc#gref>

Medicines.org.uk. 2022. [online] Available at: < [Accessed 5 January 2022].

https://www.medicines.org.uk/emc/files/pil.10145.pdf>

Accessdata.fda.gov. 2022. [online] Available at: < [Accessed 5 January 2022].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/021077s029lbl.pdf>
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Information on this page was last updated on 11 Jan 2022

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We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.