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Seretide 250 Evohaler
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Seretide 250 Evohaler

Manufactured byGlaxosmithkline Pharmaceuticals Ltd.
ContainsFluticasone propionate (250 mcg) + Salmeterol (25 mcg)
Description
Seretide 250 Evohaler is a combination of Fluticasone propionate and Salmeterol. This medicine is used to relieve symptoms such as wheezing, shortness of breath, chest tightness, breathing difficulties, coughing, etc. caused by asthma and chronic obstructive pulmonary disease (lung disorder in which the airflow is blocked which leads to breathing difficulty). It works by relaxing and widening the muscles in your airways. Seretide 250 Evohaler may cause some side effects like sore throat, cough, headache and hoarse voice. Inform your doctor if the side effects become severe or persist for a long time. Seretide 250 Evohaler should be used in the dose and duration advised by your doctor. For the ease of remembering, use it around the same time every day. Even if you see an improvement in your condition, do not stop taking it. If you discontinue the use of this medicine early, your symptoms may reoccur. It should not be used to relieve sudden asthma attacks. Seretide 250 Evohaler should not be used if you are allergic to it. Inform your doctor about any other health issues like liver, kidney, heart troubles or if you are undergoing any medical treatment before taking this medicine. Consult your doctor before taking this medicine if you are pregnant, planning to become pregnant, or are breastfeeding. This medicine should not be used in children below 12 years of age.
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Side effects

Major & minor side effects for Seretide 250 Evohaler

  • Soreness in the mouth, throat, or tongue
  • Headache
  • Muscle cramps
  • Joint pain
  • Skin rash
  • Shortness of breath
  • Sweating
  • Sleep disturbances
  • Swelling of face, lips, mouth, and tongue
  • Irregular heartbeat
  • White patches in the mouth or on the tongue

Uses of Seretide 250 Evohaler

What is it prescribed for?

  • Asthma - Maintenance
  • Chronic obstructive pulmonary disease
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for Seretide 250 Evohaler to show its effects is not clinically known.
  • How long do the effects of this medicine last?
    The amount of time for which Seretide 250 Evohaler remains active in your body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with your doctor before using this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with your doctor before using this medicine. If the medicine is used, the infant should be monitored closely for any undesirable side effects.

Allergy

Avoid taking Seretide 250 Evohaler if you are allergic to it. Allergic reactions are very rare to this medicine. Seek immediate medical attention if you notice any symptoms of allergic reactions such as skin rash, itching/swelling (of your face/tongue/throat), breathing difficulties, etc.

Status asthmaticus

Status asthmatics is a severe attack where the airways of your lungs are constricted. Seretide 250 Evohaler is not recommended for use in status asthmatics as first-line therapy because it is not effective in treating this condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with your doctor before using this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with your doctor before using this medicine. If the medicine is used, the infant should be monitored closely for any undesirable side effects.
General warnings

Hypokalemia

This medicine should be used with caution if you have a known history of hypokalemia (low blood potassium levels) due to the increased risk of worsening your condition. Close monitoring of potassium levels, appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary in some cases based on your clinical condition.

Seizure disorder

This medicine should be used with caution if there is a known history of seizures (fits) due to the increased risk of worsening your condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on your clinical condition.

Thyrotoxicosis

This medicine should be used with caution if there is a known history of thyrotoxicosis (a condition where there is an increase in thyroid hormones) due to the increased risk of worsening your condition. You may require a dose adjustment and more frequent clinical monitoring to safely use this medicine. Replacement with a suitable alternative may be necessary based on your clinical condition.

Use in pediatrics

This medicine is not recommended for use in children less than 12 years of age since the safety and efficacy data of use are not clinically established.

Growth retardation

This medicine may cause growth retardation in some children. Therefore, children receiving this medicine should be monitored closely with regard to growth parameters. Replacement with a suitable alternative may be necessary in some cases based on your clinical condition.

Candida infection

Before using Seretide 250 Evohaler, it is advisable to get examined for candidiasis. Candidiasis is an infection with the fungus Candida albicans as seen as a thick white coating over the tongue and the insides of your cheeks. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required based on your clinical condition.

Liver impairment

This medicine should be used with caution if there is a known history of liver function impairment due to the increased risk of worsening your condition. Regular monitoring of liver function tests, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on your clinical condition.

Missed Dose

The missed dose should be inhaled as soon as possible. It is advisable to skip the missed dose if it is already time for your next scheduled dose. Do not use extra medicine to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact your doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Atazanavir

Amprenavir

Itraconazole

Disease interactions

Cardiovascular disorders

This medicine should be used with caution if there is a known history of cardiovascular disorders due to the increased risk of serious side effects. Report any unusual symptoms to the doctor immediately. You may require a dose adjustment and more frequent clinical monitoring to safely use this medicine. An alternative treatment option may be necessary in some cases based on your clinical condition.

Hyperadrenocorticism

This medicine should be used with caution if there are high levels of adrenal hormones in your body. Appropriate dose adjustments or replacement with a suitable alternative may be required based on your clinical condition.

Infections

This medicine should be used with extreme caution if there are active infections since this medicine can suppress the immune system. This risk is especially higher if you are given high doses of this medicine for a prolonged period. Appropriate dose adjustments or replacement with a suitable alternative may be required based on your clinical condition.

Ocular herpes infection

This medicine should be used with caution if you have an ocular herpes infection. Appropriate dose adjustments or replacement with a suitable alternative may be required based on your clinical condition.

Ocular Toxicities

This medicine should be used with extreme caution if you have a history of cataracts, glaucoma (increased intraocular pressure). Appropriate dose adjustments or replacement with a suitable alternative may be required based on your clinical condition.

Osteoporosis

This medicine should be used with caution if you have osteoporosis (bones become weak and brittle) since it may cause loss of bone density and further worsen the existing condition. Close monitoring of bone density, appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required based on your clinical condition.

Hepatic impairment

This medicine should be used with caution if you have liver function impairment due to the increased risk of severe side effects. Close monitoring of liver function may be required during treatment with this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on your clinical condition.

Diabetes

This medicine should be used with caution if you have diabetes (increased risk of altered blood sugar levels). You may require a dose adjustment and more frequent monitoring of blood sugar levels to safely use this medicine. Replacement with a suitable alternative may be necessary based on your clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Administer this medicine exactly as prescribed by your doctor. Follow all the instructions given in the information leaflet or the package insert. Do not use in larger or smaller amounts than prescribed. Consult your doctor if you experience any undesirable side effects. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
Seretide 250 Evohaler is a combination of Fluticasone propionate and Salmeterol. Fluticasone propionate works by inhibiting the release of certain substances in your body that cause inflammation (swelling, redness, pain, etc.). Salmeterol relaxes and opens the blocked air passages leading to the lungs; this improves the amount of airflow to the lungs and makes breathing easier. Their combination is thus more effective for the maintenance treatment of asthma and chronic obstructive pulmonary disease (COPD).
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Bronchodilator combinations

Schedule

Schedule H

Medicines.org.uk. 2021. [online] Available at: < [Accessed 29 November 2021].

https://www.medicines.org.uk/emc/files/pil.10145.pdf>

2021. [online] Available at: < [Accessed 29 November 2021].

https://www.nps.org.au/medicine-finder/fluticasone-and-salmeterol-cipla-250-25-inhaler-cfc-free>

Drugs, H., 2021. Fluticasone Oral Inhalation: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 29 November 2021].

https://medlineplus.gov/druginfo/meds/a601056.html>

Drugs, H., 2021. Salmeterol Oral Inhalation: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 30 August 2021].

https://medlineplus.gov/druginfo/meds/a695001.html>
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Information on this page was last updated on 7 Dec 2021

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