Salkef 250 MG Tablet

Manufactured bySalud Care (India) Pvt. Ltd.
ContainsCefuroxime
Description

Salkef 250 MG Tablet is a broad-spectrum antibiotic used to treat a variety of conditions such as Lyme disease; infections of the ears, lungs, urinary tract, etc. caused by bacteria. This medicine should be used with caution in patients with a history of kidney diseases.

Side effects

Major & minor side effects for Salkef 250 MG Tablet

  • Diarrhea
  • Chills
  • Headache
  • Itching of vagina or genital area
  • Chest pain
  • Difficult or painful urination
  • Shortness of breath
  • Change in taste
  • Abdominal pain
  • Acid or sour stomach

Uses of Salkef 250 MG Tablet

What is it prescribed for?

  • Pharyngitis/Tonsilitis
  • Acute Bacterial Otitis Media
  • Sinusitis
  • Bronchitis
  • Skin and Structure Infection
  • Cystitis
  • Pyelonephritis
  • Lyme disease
  • Gonococcal Infection
Read More
Concerns

Commonly asked questions

  • Onset of action
    The peak effect of Cefuroxime (the main constituent of Salkef 250 MG Tablet) can be observed within 2 to 3 hours after the oral dose, 15 to 60 minutes after an intramuscular dose, and 2 to 3 minutes after an intravenous dose.
  • Duration of effect
    The effect of this medicine lasts for an average duration of approximately 4 to 8 hours.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit forming tendency has been reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking/receiving this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving/taking this medicine. If the medicine is used, close monitoring of the infant for any undesired side effects is necessary.

Allergy

This medicine is not recommended for use if the patient has a known allergy to cefuroxime or any other Beta-lactam antibiotics like penicillins and cephalosporins.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking/receiving this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving/taking this medicine. If the medicine is used, close monitoring of the infant for any undesired side effects is necessary.
General warnings

Hypersensitivity reactions

This medicine may cause serious and occasionally fatal hypersensitivity reactions including anaphylactic shock in some patients. This risk is especially high in patients with a history of sensitivity to multiple allergens. If an anaphylactic reaction occurs, the treatment should be discontinued immediately and appropriate corrective measures should be undertaken.

Clostridium difficile-associated Diarrhea

Antibiotic therapy will cause an imbalance in the normal microbial flora of the large intestine, which may promote the growth of a bacteria called Clostridium difficile and you may experience severe diarrhea as a result. Report any such incidence to the doctor on priority and avoid usage of this medicine in these cases.

Impaired kidney function

This medicine should be used with caution in patients with a known history of renal impairment due to the increased risk of severe adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Drug-resistance

Usage of this medicine without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that are drug resistant.

Use in pediatrics

Use of Salkef 250 MG Tablet is not recommended for infants less than 3 months of age.

Jarisch-Herxheimer reaction

This medicine may cause Jarisch-Herxheimer reaction in some patients when it is used for treating Lyme disease. This reaction is characterized by symptoms such as fever, chills, headache, dizziness, increased heart rate, etc. This reaction usually subsides on its own. Appropriate corrective measures or dose adjustments may be necessary based on the clinical condition of the patient.

Missed Dose

Oral forms: The missed dose should be taken as soon as possible. It is advisable to skip the missed dose if it is already time for your next scheduled dose. Do not double your dose to make up for the missed one. Injection: Since this medicine is administered by a qualified healthcare professional in the clinical or hospital setting, the likelihood of a missed dose is very low.

Overdose

Oral forms: Seek emergency medical attention or contact your doctor in case of an overdose. Injection: Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Amikacin

Chloramphenicol

Ethinyl Estradiol

Cholera Vaccine

Furosemide

Disease interactions

Gastrointestinal Disorders

This medicine should be used with extreme caution in patients having a history of gastrointestinal diseases, particularly colitis, since it may worsen the patient's condition. Report any incidence of severe diarrhea, abdominal pain, blood in stools, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Liver Disease

This medicine should be used with caution in patients with a history of liver diseases or a family history of liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function is recommended during treatment with this medicine. Report any undesired side effects to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Seizure disorders

This medicine should be used with caution in patients with a history of seizure disorder or a family history of seizures due to the increased risk of recurrent seizures. Therapy should be discontinued if the patient experiences a seizure episode due to this medicine. Appropriate corrective measures and/or replacement with a suitable alternative may be necessary in some cases based on the clinical condition of the patient.

Impaired kidney function

This medicine should be used with extreme caution in patients with a known history of renal diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.
Food interactions
Information not available.
Lab interactions

Ferricyanide test

Inform the doctor if you are advised to have this test when you are undergoing treatment with this medicine. This medicine may result in false-negative results for this test. Alternative tests should be used for testing blood glucose based on the clinical condition.
Oral forms: Take this medicine as advised by your doctor. You may take this medicine with or without food. Do not take in larger amounts than advised. Injection: This medicine should be administered by a qualified healthcare professional in the clinical or hospital setting. Inform the doctor if you have a known history of allergy to this medicine. Report to the doctor all your current medicines as well as your medical conditions before receiving this medicine. Report any undesired side effects to the doctor promptly.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Salkef 250 MG Tablet stops the growth and multiplication of bacteria.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Second generation cephalosporins

Schedule

Schedule H

DailyMed - Cefuroxime axetil tablet [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 21 February 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=faef39e9-d793-4191-a728-310f6fab759d

Cefuroxime: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 21 February 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a601206.html

[Internet]. 2017 [cited 21 February 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/22534#PRODUCTINFO

Prescribing medicines in pregnancy database [Internet]. Therapeutic Goods Administration (TGA). 2017 [cited 21 February 2017]. Available from:

https://www.tga.gov.au/prescribing-medicines-pregnancy-database#searchname
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