DELIVERY LOCATION
560076
DELIVERY LOCATION
560076
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Prokem 250 MG Tablet

Manufacturer
Monokem Laboratories
Composition
Ciprofloxacin
Prescription
Required

Description

Prokem 250 MG Tablet is an antibiotic that is used to treat a variety of bacterial infections such as bronchitis, pneumonia, gonococcal infection, etc. This medicine is not recommended for use in case of a common cold, flu, or other viral infections since it is active against infections caused by bacteria only. This medicine should be used with caution in the elderly population as it increases the risk of tendinitis and tendon rupture.

Uses of Prokem 250 MG Tablet

What is it prescribed for?

  • Pneumonia

    This medicine is used in the treatment of community-acquired pneumonia which is a most common type of lung infection caused by Streptococcus pneumoniae or Haemophilus influenzae.

  • Bronchitis

    This medicine is used in the treatment of bronchitis which is an inflammation of the lining of the bronchial tubes caused by Streptococcus pneumoniae, Haemophilus influenzae, and some Mycoplasma pneumoniae.

  • Cystitis

    This medicine is used in the treatment of cystitis which is a bladder infection caused by E.coli, Pseudomonas aeruginosa, Enterococci, Klebsiella pneumoniae, etc.

  • Prostatitis

    This medicine is used in the treatment of Prostatitis (inflammation of the prostate gland that produces semen) caused by Escherichia coli, Pseudomonas and Enterococcus species.

  • Gonococcal infection

    This medicine is used in the treatment of a gonococcal infection, which is a sexually transmitted bacterial infection caused by Neisseria gonorrhoeae.

  • Joint infection

    This medicine is used in the treatment of bone and joint infections caused by Enterobacter cloacae, Pseudomonas aeruginosa, Serratia marcescens, etc.

  • Pneumonia with cystic fibrosis

    This medicine is used in the treatment of pneumonia with cystic fibrosis, an inherited disease that causes thick mucus to build up in the lungs and promotes the growth of bacteria such as Staphylococcus aureus and Hemophilus influenzae.

  • Pyelonephriits

    This medicine is used in the treatment of pyelonephritis which is a type of kidney infection caused by E. coli, Pseudomonas aeurginosa, Enterococci, Klebsiella pneumoniae, etc.

  • Inhalation Anthrax

    This medicine is used in the treatment of anthrax which is a rare but serious bacterial illness caused by Bacillus anthracis.

  • Plague

    This medicine is used in the treatment of plague which is a serious bacterial illness caused by Yersinia pestis.

Side effects

Major & minor side effects for Prokem 250 MG Tablet

  • Diarrheasevere
  • Abdominal painsevererare
  • White patches in the mouth or on the tonguesevererare
  • Joint painsevererare
  • Black or tarry stoolssevererare
  • Fever with chillssevererare
  • Chest tightnesssevererare
  • Ringing or buzzing in the earssevererare
  • Muscle painsevererare
  • Numbness of the handssevererare
  • Swelling of face, lips, eyelids, tongue, hands and feet severerare
  • Runny Nose
  • Sneezing
SEVERE
Contact your doctor immediately if any of these symptoms are experienced on a regular basis.
RARE
Observed in a small fraction of population.
This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Highlights

Commonly asked questions for Prokem 250 MG Tablet

Onset of action

The peak effect of this medicine can be observed within 1 to 2 hours of administration of the dose.

Duration of effect

The effect of this medicine lasts for an average duration of 12 to 20 hours.

Safe with alcohol?

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Is it habit forming?

No habit-forming tendencies were reported.

Usage in pregnancy?

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Usage while breast-feeding?

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. If the medicine is used, the infant should be monitored closely for any adverse effects.

Substitutes

List of substitutes for Prokem 250 MG Tablet

Below is the list of medicines, which have the same composition, strength and form as Prokem 250 MG Tablet, and hence can be used as its substitute.
Baycip 250 MG Tablet
Bayer Pharmaceuticals Pvt. Ltd.
Cipbact 250 MG Tablet
Unichem Laboratories Ltd.
Ciprowin 250 MG Tablet
Alembic Ltd.
Gercip 250 MG Tablet
Zydus Cadila
Zucipro 250 MG Tablet
Zuventus Healthcare Ltd.

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When not to use?

Contraindications of Prokem 250 MG Tablet

  • Allergy

    This medicine is not recommended for use in patients with a known allergy to ciprofloxacin, any other fluoroquinolones, or any other inactive ingredients present along with it.

  • Tendinitis or tendon rupture

    This medicine is not recommended for use in patients with a known history of tendon rupture or tendinitis (a condition in which the tissue connecting muscles to the bones becomes inflamed) due to the increased risk of worsening of the patient's condition.

  • Myasthenia gravis

    This medicine is not recommended for use in patients with a known history or family history of myasthenia gravis (weakness and rapid fatigue of muscles under voluntary control) due to the increased risk of worsening of the patient's condition.

Dosage

  • Missed Dose

    Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

  • Overdose

    Seek emergency medical treatment or contact the doctor in case of an overdose.

Interactions

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

  • Description

    - Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Instructions

    - Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Medicine

Disease interactions

  • Central nervous system disorders

    severe
    This medicine should be used with extreme caution in patients with a history of seizure disorder and other central nervous system abnormalities since it may worsen the patient's condition. Report any incidence of tremors, restlessness, anxiety, confusion, hallucinations, etc., to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient. It is advisable to avoid using caffeine-containing products while on therapy with fluoroquinolones.

  • Colitis

    severe
    This medicine should be used with extreme caution in patients having a history of gastrointestinal diseases, particularly colitis, since it may worsen the patient's condition. Report any incidence of severe diarrhea, abdominal pain, blood in stools, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

  • QT Prolongation

    severe
    This medicine should be used with extreme caution in patients with a history of QT prolongation due to the increased risk of worsening of the patient's condition. This risk is especially higher in patients with heart diseases or electrolyte disturbances and elderly patients. Report any incidence of discomfort in the chest, heart palpitations, etc., to the doctor on priority. Close monitoring of heart function and vital signs, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

  • Renal impairment

    moderate
    This medicine should be used with caution in patients with renal diseases due to the increased risk of severe adverse effects. Report any unusual symptoms to the doctor immediately. Close monitoring of kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Food interactions

  • The desired effect of this medicine may not be obtained if it is consumed with any dairy products. You are advised to consume this medicine at least 1 hour before or 2 hours after consuming dairy products to avoid their interaction.

Lab interactions

  • Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.

General Instructions

Take this medicine with or without food, as directed by your doctor. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.

Warnings

Warnings for special population

  • Pregnancy

    - This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

  • Breast-feeding

    - This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. If the medicine is used, the infant should be monitored closely for any adverse effects.

General warnings

  • Tendinitis and tendon rupture

    - Use of this medicine will increase the risk of developing tendinitis or tendon rupture during the treatment or several months after the treatment. This may affect your shoulders, hands, ankles, or other parts of your body. You are at a higher risk if you are more than 60 years of age or if you have undergone a transplant of kidney, heart, or lung. You are also at a higher risk if you are on corticosteroids such as dexamethasone, methylprednisolone, or prednisone. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

  • Drug-resistance

    - Usage of this medicine without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing benefits and may even cause toxicity. It may also increase the risk of development of bacteria that are drug resistant.

  • Alternative treatment

    - This medicine can be used to treat an acute bacterial exacerbation of chronic bronchitis or uncomplicated cystitis, but only as a last resort. This drug should be used only if you have no alternative treatment options for the above-mentioned conditions.

  • Diarrhea

    - Antibiotic therapy will cause an imbalance in the normal microbial flora of the large intestine, which may promote the growth of a bacteria called Clostridium difficile and you may experience severe diarrhea as a result. Report any such incidence to the doctor on priority and avoid usage of this medicine in such cases.

  • Driving or Operating machinery

    - Use of this medicine may rarely cause symptoms such as blurred vision, drowsiness, dizziness, etc. in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Other details

  • Can be taken with or without food, as advised by your doctor
  • To be taken as instructed by doctor
  • May cause sleepiness

How it works

This medicine works by inhibiting an enzyme required for the bacterial DNA to replicate. This blocks the multiplication and growth and results in the eventual death of the bacteria.

Legal Status

Approved
Approved
Approved
Approved

Classification

Category
Quinolones
Schedule
Schedule H

References

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Information on this page was last updated on 19 Apr 2018

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Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.