Pregcert 300 MG Tablet SR

Manufactured byKoye Pharmaceuticals Pvt. Ltd.
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Valid on prescription medicines, only for first time user
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Description

Pregcert 300 MG Tablet SR is obtained from plant sources and has a similar action to the female hormone, progesterone. It is used to correct menstrual disorders caused due to a deficiency of this hormone in the body. It is also used as a component in hormone replacement therapy and for maintenance of early pregnancy under specific circumstances.

Side effects

Major & minor side effects for Pregcert 300 MG Tablet SR

  • Chest pain and discomfort
  • Fever and chills
  • Difficulty in passing urine
  • Breast pain and tenderness
  • Muscle or joint pain
  • White or brownish discharge from the vagina
  • Headache
  • Dizziness
  • Depression
  • Viral infections
  • Breast lumps
  • Loss of vision or blurred vision
  • Unexpected vaginal bleeding
  • Convulsions (seizures)
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Constipation or diarrhea
  • Nausea or Vomiting
  • Hot flashes
  • Hair loss or thinning of the hair

Uses of Pregcert 300 MG Tablet SR

What is it prescribed for?

  • Post menopausal hormonal replacement therapy
  • Amenorrhoea
  • Dysfunctional uterine bleeding
  • Endometrial hyperplasia
  • Progesterone deficiency during pregnancy
  • Premenstrual syndrome
  • Contraception
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Concerns

Commonly asked questions

  • Onset of action
    The time taken for this medicine to show it's effect is subject to vary from one person to another.
  • Duration of effect
    The duration of action of this medicine is subject to vary based on factors like age, dosage form etc.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is recommended for use in pregnancy only if the need is clinically established. Consult your doctor before using this medicine.
  • Usage while breast-feeding?
    Use of this medicine is not recommended if you are breastfeeding. This medicine can pass into the breast milk and may harm the nursing infant.

Allergy

This medicine is not recommended for use if you have a known history of allergy to progesterone or any other ingredient present with it. This medicine might contain peanut oil and should never be used by patients who are allergic to peanuts.

Abnormal vaginal bleeding

This medicine is not recommended for use if you have an abnormal bleeding episode which has not been diagnosed by a doctor.

Breast cancer

This medicine is not recommended for use if you have breast cancer or are suspected to have it. It is not recommended for use if the patient has a history of breast cancer.

Miscarriage

This medicine is not recommended for use if the patient has had an incomplete miscarriage or missed abortion recently.

Heart and blood vessel disorder

This medicine is not recommended for use in patients having an active or historic instance of stroke or heart attack. It should not be used by patients having an active or historic clotting disorder.

Liver disease

This medicine is not recommended for use in patients having a liver disease or impairment of normal liver function.

Second and third trimester of pregnancy

This medicine is not recommended for use during the late stages of the second trimester and for the entire third trimester of pregnancy. It should not be used during pregnancies where luteal phase progesterone deficiency is not clinically established.
Warnings for special population

Pregnancy

This medicine is recommended for use in pregnancy only if the need is clinically established. Consult your doctor before using this medicine.

Breast-feeding

Use of this medicine is not recommended if you are breastfeeding. This medicine can pass into the breast milk and may harm the nursing infant.
General warnings

Dizziness

Use of this medicine can cause dizziness and impair the ability to perform tasks requiring cognition and alertness. Caution is advised while driving or performing other tasks that demand a high level of mental alertness. You are advised to take the medicine at recommended times to avoid any such effect.

Breast cancer

Use of this medicine in conjugation with estradiol for hormone replacement therapy has been associated with instances of breast cancer and hence caution is advised. This medicine should be given with extreme caution to patients with a previous or active case of breast cancer.

Blood clotting disorders

Use of this medicine is not recommended for patients having a clotting disorder. It is advised to undergo a test to confirm if the medicine can be safely used. Report any instance of such disease to the doctor.

Bleeding disorders

Use of this medicine is not recommended if you have severe undiagnosed vaginal bleeding.

Fluid retention

Use of this medicine is known to cause mild to moderate amounts of fluid retention in the body. Hence, caution is advised while administering in patients with diseases like epilepsy, asthma, migraine, heart and blood vessel disorders, kidney impairment etc.

Depression

Use of this medicine is known to cause a varying amount of depression in different individuals. It should be carefully prescribed in patients having a history of depression. Use of this medicine should be discontinued if the depressive episode becomes more frequent and severe.

Metabolic disorders

Use of this medicine is known to interfere with the fat and sugar metabolism in the body. it should be prescribed with caution in patients suffering from metabolic disorders like diabetes, high cholesterol etc.

Vision abnormalities

Use of this medicine can cause blurring of vision and other effects on the eye like proptosis, diplopia etc. Patients should be carefully examined to confirm if they can safely use this medicine. Any side effects like blurred vision, excessive drying of eyes should be reported to the doctor.

Other medicine

This medicine can interact with a large number of medicines and hence it is recommended to report the use of all medicines including supplements and herbs to the doctor. The vaginal form of this medicine should be used with other gels or ointments after a sufficient time gap.

Liver disease

This medicine should be used with caution in patients having a liver disease or an impairment of normal liver function.

Peanut allergy

This medicine is not recommended for use if you have a known history of allergy to peanuts.

Use during pregnancy

This medicine should be used during pregnancy only when advised by the consulting doctor and the clinical evidence points towards a deficiency of luteal progesterone hormone during the early stages.

Missed Dose

Take the missed dose as soon as you remember unless it is almost time for the next scheduled dose. Contact your doctor if you have missed more than one dose.

Overdose

Contact your doctor if an overdose is suspected. The short-term effects of an overdose could be a headache, dizziness, nausea, and vomiting.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Carbamazepine

Ketoconazole

Insulin

Phenobarbital

Venetoclax

Edoxaban

Disease interactions

Breast cancer

Use of this medicine is not recommended for patients having an active case of breast cancer or are suspected of having it. Report all such instance including occurrence in the past to the doctor so that an informed decision can be taken in regards to the future treatment plan.

Liver disease

Use of this medicine is not recommended if the patient has a liver disease or the normal liver function is impaired.

Thromboembolism

Use of this medicine is not recommended in patients having a clotting disorder in which the formed clot moves from one place and lodges in another place.

Depression

This medicine should be used with caution in patients having episodes of depression or having a history of depression especially when estrogen is also administered in combination.

Retinal thrombosis

Use of this medicine can sometimes cause a loss of vision by blocking the flow of blood from the retina to the heart. Hence caution should be exercised while using it and any abnormality in vision should be reported to the doctor.
Food interactions
Information not available.
Lab interactions

Blood coagulation tests

Report the use of progesterone to the doctor before undergoing a test to measure the coagulation time. Use of this medicine can interfere with the test results.

Liver function tests

Report the use of progesterone to the doctor before undergoing a liver function test. Use of this medicine can interfere with the test and give false results.

Thyroid function tests

Report the use of progesterone to the doctor before undergoing a thyroid function test. This medicine can interfere with the test and give a false positive result.
Take Pregcert 300 MG Tablet SR as prescribed by the doctor. Follow all dosing instruction mentioned on the label. It is advised to take this medicine at bedtime with sufficient quantity of water. Do not take this medicine for durations shorter or longer than recommended by your doctor. You are advised to regularly examine your breasts for the presence of lumps while using this medicine.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine acts by mimicking the actions of progesterone and helps in regulation of ovulation and menstruation in women of childbearing age. Similarly, it is used in hormonal replacement therapy for women who have passed menopause and have not had a uterus removal surgery done.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Progestins

Schedule

Schedule H

[Internet]. 2017 [cited 5 October 2017]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/019781s013lbl.pdf

[Internet]. 2017 [cited 4 April 2017]. Available from:

http://www.medsafe.govt.nz/profs/Datasheet/u/UtrogestanSunflowerOilcap.pdf

DailyMed - Crinone- progesterone gel [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 4 April 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2c8ffbd2-6b7a-42c7-b29e-e4de69dad9e6

[Internet]. 2017 [cited 5 October 2017]. Available from:

http://www.ferringusa.com/wp-content/uploads/2016/09/EndometrinPI-9.2016.pdf

Luteal Phase Support in assisted reproductive technology treatment: focus on Endometrin® (progesterone) vaginal insert [Internet]. PubMed Central (PMC). 2017 [cited 5 October 2017]. Available from:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695240/
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