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Phosome 25 mg Injection

Manufactured by: Cipla Ltd.
Prescription Required: Yes
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Description

Phosome 25 mg Injection is an antifungal medicine used to treat serious and potentially life-threatening infections caused by different fungal species. The liposomal form of this medicine has been shown to be less nephrotoxic than the conventional form. Incidences of infusion-related adverse reactions associated with the liposomal form are also fewer than that of the conventional form.

Side effects

Major & minor side effects for Phosome 25 mg Injection

  • Irregular heart beatsevere
  • Fever and chills
  • Diarrhea
  • Decreased potassium levelssevere
  • Anemiasevere
  • Cough
  • Abdominal pain
  • Headache
  • Pain at injection sitesevere
  • Nausea and Vomiting
  • Chest painsevere
SEVERE
Contact your doctor immediately if any of these symptoms are experienced on a regular basis.
RARE
Observed in a small fraction of population.
This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Highlights

Commonly asked questions for Phosome 25 mg Injection

Onset of action

The amount of time required for this medicine to show its action is not clinically established.

Duration of effect

The amount of time for which this medicine remains active in the body is not clinically established.

Safe with alcohol?

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Is it habit forming?

No habit forming tendency has been reported.

Usage in pregnancy?

This medicine is recommended for use in pregnant women only if absolutely necessary. Discuss all the risks and benefits with your doctor before using this medicine.

Usage while breast-feeding?

This medicine is relatively safe for use in breastfeeding women. However, all the risks and benefits should be discussed with the doctor before using this medicine.

Substitutes

List of substitutes for Phosome 25 mg Injection

Below is the list of medicines, which have the same composition, strength and form as Phosome 25 mg Injection, and hence can be used as its substitute.
Lambin 25 mg Injection
Sun Pharma Laboratories Ltd.

What is it prescribed for?

Uses of Phosome 25 mg Injection

  • Invasive Aspergillosis

    This medicine is used for the treatment of infections caused by fungi of the Aspergillus species that tend to spread quickly.

  • Candidemia

    This medicine is used for the treatment of candidemia, a condition where the fungi of the Candida species are present in the blood.

  • Cryptococcosis

    This medicine is used for the treatment of fungal infections caused by Cryptococcus species.

  • Febrile Neutropenia

    This medicine is used to treat the development of fever in patients with neutropenia (low number of neutrophils in the blood).

  • Cryptococcal Meningitis

    This medicine is used for the treatment of fungal infections of the membranes surrounding the spinal cord and brain caused by Cryptococcus species.

  • Leishmaniasis

    This medicine is used for the treatment of Leishmaniasis, a parasite infection caused by the Leishmania species.

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When not to use?

Contraindications of Phosome 25 mg Injection

  • Allergy

    This medicine is not recommended for use in patients with a known allergy to amphotericin B or any other components present along with it.

Dosage

  • Missed Dose

    Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of missing a dose is very low.

  • Overdose

    Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.

Interactions

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

  • Description

    - Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Instructions

    - Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Medicine

Disease interactions

  • Disease

    Information not available.

Food interactions

  • Information not available.

Lab interactions

  • Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.

General Instructions

This medicine should be administered only by a qualified healthcare professional. Carefully follow all the instructions given by your doctor. Report to the doctor all your current medicines as well as your medical conditions before receiving this medicine.

Warnings

Warnings for special population

  • Pregnancy

    - This medicine is recommended for use in pregnant women only if absolutely necessary. Discuss all the risks and benefits with your doctor before using this medicine.

  • Breast-feeding

    - This medicine is relatively safe for use in breastfeeding women. However, all the risks and benefits should be discussed with the doctor before using this medicine.

General warnings

  • Anaphylaxis

    - This medicine may cause serious anaphylactic reactions. Appropriate corrective measures should be undertaken in the event of any anaphylactic reactions. Therapy may be discontinued based on the clinical condition.

  • Noninvasive fungal infections

    - This medicine is not recommended to treat noninvasive fungal infections in patients with normal neutrophil counts.

  • Infusion reactions

    - This medicine may cause infusion reactions such as a headache, fever, chills, loss of appetite, nausea, vomiting, breathing problems, or dizziness with the first few doses. These reactions usually diminish with subsequent doses.

  • Rapid intravenous infusion

    - Rapid intravenous infusion of this medicine should be avoided due to the increased risk of serious adverse effects such as hypotension, hypokalemia, arrhythmias, and shock.

Other details

  • Usage does not depend on food timings
  • To be taken as instructed by doctor
  • Does not cause sleepiness

How it works

Phosome 25 mg Injection works by blocking the action of a certain vital component of the fungal cell wall. This results in disruption of cell membrane and death of the fungus.

Legal Status

Approved
Approved
Approved
Approved

Classification

Category
Polyenes
Schedule
Schedule H

References

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Information on this page was last updated on 9 Sep 2017

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Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.