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Monocin 300 mg Tablet
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Monocin 300 mg Tablet

Manufactured byOverseas Healthcare Pvt. Ltd.
ContainsRifampicin
Description
Monocin 300 mg Tablet is an antibiotic that is effective against tuberculosis (TB) and meningitis (swelling of the protective layers of the brain and spinal cord) caused by bacteria. Both are severe and major bacterial infections of the lungs and the brain. It can be used alone or in combination with other medicines to form the standard therapy for tuberculosis known as DOTS (Directly observed therapy). Monocin 300 mg Tablet has some side effects such as anaemia, headache, dizziness, vomiting, nausea, and fever. Seek medical help only if these symptoms do not subside or become severe. It is advisable to avoid taking this medicine if you are allergic to it. Your tears, urine and other secretions may turn reddish orange while you are taking Monocin 300 mg Tablet. Avoid using contact lenses as they may become discoloured. This reddish discolouration is completely normal and harmless. Avoid driving or operating machinery as it may cause dizziness in some patients. Monocin 300 mg Tablet should be taken on an empty stomach or 2 hours after the meal as the food decreases its absorption. Your doctor will decide the dose and duration of this medicine based on the severity and location of the infection. Ensure to complete the entire course and do not stop taking it on your own. Stopping it early may make the infection reoccur and be difficult to treat. DOTS guidelines are followed if the treatment is for tuberculosis. Monocin 300 mg Tablet should be used with caution if you have liver and stomach/intestinal disease. To make sure this medicine is safe for you, share your entire medical and medication history with your doctor. Inform your doctor if you are pregnant, planning a pregnancy or are breastfeeding.
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Side effectsConcernsUsageRelated products

Substitutes

List of substitutes for Monocin 300 mg Tablet

Macox 300 mg Tablet
Macleods Pharmaceuticals Pvt. Ltd.

Side effects

Major & minor side effects for Monocin 300 mg Tablet

  • Abdominal pain
  • Dizziness
  • Headache
  • Yellow colored eyes or skin
  • Nausea and Vomiting
  • Skin rash
  • Loss of appetite
  • Unusual behavior
  • Muscle pain
  • Weakness
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Chest pain
  • Irregular heartbeat
  • Increased blood bilirubin

Uses of Monocin 300 mg Tablet

What is it prescribed for?

  • Tuberculosis
  • Meningococcal Meningitis
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    Monocin 300 mg Tablet starts to show its action in 1-3 hours. However, you may start feeling well in few days to weeks.
  • How long do the effects of this medicine last?
    The amount of time for which the effects of Monocin 300 mg Tablet remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    Monocin 300 mg Tablet has no habit forming tendency.
  • Can this medicine be taken during pregnancy?
    Monocin 300 mg Tablet is not recommended for use in pregnant women as it can harm the developing foetus. Discuss the benefits and risks with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    Monocin 300 mg Tablet passes into the breastmilk. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.

Allergy

It is recommended to avoid taking Monocin 300 mg Tablet if you are allergic to it. Seek an immediate medical attention if you notice any symptoms of allergic reactions such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulties, etc.

Anti viral medications

Monocin 300 mg Tablet is not recommended for use if you are receiving antiviral therapy because it may reduce the effects of antiviral medications and may lead to the development of viral resistance. These medicines together can also cause liver damage.
Warnings for special population

Pregnancy

Monocin 300 mg Tablet is not recommended for use in pregnant women as it can harm the developing foetus. Discuss the benefits and risks with the doctor before taking this medicine.

Breast-feeding

Monocin 300 mg Tablet passes into the breastmilk. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.
General warnings

Diabetes

Monocin 300 mg Tablet should be used with caution if there is a history of diabetes as it may alter blood glucose levels. Close monitoring of blood glucose levels, dose adjustments, or replacement with a suitable alternative may be required based on your clinical condition.

Antibiotic-resistance

Usage of this medicine without sufficient proof of a bacterial infection should be avoided. Improper dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of developing bacteria that are antibiotic-resistant.

Other uses

Your doctor may prescribe Monocin 300 mg Tablet for indications other than those stated above in certain specific circumstances, especially if other medicines are not effective. All the risks and benefits should be discussed with the doctor in such cases.

Missed Dose

If you have missed Monocin 300 mg Tablet dose, make sure that you remember to take the next dose on time. Do not take two doses together to make up for a forgotten dose.

Overdose

Never take Monocin 300 mg Tablet more than the prescribed dose. If you suspect that you have taken an overdose of this medicine, go to the emergency department of your local hospital.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Clopidogrel

Propranolol

Warfarin

Atorvastatin

Live cholera vaccine

Diltiazem

Cyclosporine

Disease interactions

Liver Disease

Monocin 300 mg Tablet is converted into its active form in the liver. An impaired liver cannot convert this medicine and accumulation of this medicine takes place in the liver. This accumulation may worsen the kidneys.

Colitis

Monocin 300 mg Tablet should be used with caution in patients having colitis due to the worsening of the colitis. Colitis is the swelling of the colon, a part of the intestine.

Hematopoietic disturbances

Monocin 300 mg Tablet should be used with extreme caution in patients with preexisting bone marrow depression or blood dyscrasias due to the increased risk of hematopoietic abnormalities. These abnormalities may include low red blood cells, low white blood cells, low platelet, low haemoglobin, etc.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Monocin 300 mg Tablet can be taken on an empty stomach for good results. In case of an upset stomach, it is advisable to take it with small portions of food. Your urine, tears and other secretions may become orange-red in colour. Avoid using contact lenses as they may become discoloured. Avoid taking hormone-based birth control methods as Monocin 300 mg Tablet may decrease their effectiveness. Tell your doctor immediately if you experience unusual tiredness or loss of appetite, fever or chills. Ensure that the course of treatment is completed to prevent the spread of infection. Do not break, crush or chew the tablet in your mouth.
Miscelleneous

To be taken on an empty stomach

To be taken as instructed by doctor

May cause sleepiness

How it works
Monocin 300 mg Tablet works by interfering with the bacterial DNA synthesis and stops the growth of the bacteria.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Antituberculosis agents

Schedule

Schedule H

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https://patient.inf

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https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/050420s073,050627s012lbl.pdf>

Products.sanofi.us. 2021. [online] Available at: < [Accessed 24 August 2021].

https://products.sanofi.us/rifadin/rifadin.pdf>

Pharmacology, C., 2021. Patient Information Leaflet - Rifampicin - My Medicines. [online] Mymedicines.nz. Available at: < [Accessed 24 August 2021].

https://www.mymedicines.nz/home/sheet/F7P7ZNVU7hw=?format=inline>
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Information on this page was last updated on 26 Aug 2021

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.