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MIDACIP 1.25 NASAL SPRAY
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MIDACIP 1.25 NASAL SPRAY

Manufactured byCipla Ltd.
ContainsMidazolam
Description
MIDACIP 1.25 NASAL SPRAY is a benzodiazepine medication used for the short-term treatment of seizure clusters (periods of increased seizure/fits) in individuals aged 12 years and older. This medicine is not a replacement for daily seizure medicine. MIDACIP 1.25 NASAL SPRAY may cause some side effects like sleepiness, headache, runny nose and nasal discomfort. Inform your doctor if the side effects become severe or persist for a long time. MIDACIP 1.25 NASAL SPRAY should only be used in the nose. Your doctor will provide instructions to you and your caregiver on how to identify seizure clusters and how to use the product appropriately. MIDACIP 1.25 NASAL SPRAY should not b used if you are allergic to it. Inform your doctor about all other medicines that you are taking currently and also if you have medical conditions like liver, kidney or heart problems. If you are pregnant or are breastfeeding, consult your doctor before taking this medicine.
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Side effectsConcernsUsageRelated products

Side effects

Major & minor side effects for MIDACIP 1.25 NASAL SPRAY

  • Chest pain and discomfort
  • Confusion
  • Irregular heart beat
  • Irritability
  • Nausea and Vomiting
  • Nervousness
  • Rash
  • Headache

Uses of MIDACIP 1.25 NASAL SPRAY

What is it prescribed for?

  • Seizures
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The onset of action of MIDACIP 1.25 NASAL SPRAY is rapid, with its complete effects achieved within 10 minutes of administration.
  • How long do the effects of this medicine last?
    The amount of time for which MIDACIP 1.25 NASAL SPRAY remains active in your body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol during treatment with MIDACIP 1.25 NASAL SPRAY may increase the risk of severe side effects such as confusion, dizziness, nausea, vomiting, weakness, and fainting.
  • Is this a habit forming medicine?
    MIDACIP 1.25 NASAL SPRAY may become habit-forming in some cases. Close monitoring of the patient for any changes in behaviour or mood is recommended during treatment with this medicine.
  • Can this medicine be taken during pregnancy?
    MIDACIP 1.25 NASAL SPRAY is not recommended for use during pregnancy. Discuss all the risks and benefits with your doctor before using this medicine.
  • Can this medicine be taken while breast-feeding?
    MIDACIP 1.25 NASAL SPRAY is not recommended for use in nursing mothers. Discuss all the risks and benefits with your doctor before using this medicine.

Allergy

Avoid using MIDACIP 1.25 NASAL SPRAY if you are allergic to it. Seek immediate medical attention if you notice symptoms such as skin rash, itching/swelling of the face/tongue/throat, breathing difficulty, etc.

Narrow-angle glaucoma

Narrow-angle glaucoma is a sudden rise of intraocular pressure (pressure within your eye) due to blocked drainage canals in your eyes. MIDACIP 1.25 NASAL SPRAY is not recommended for use in such cases as it can worsen your condition.
Warnings for special population

Pregnancy

MIDACIP 1.25 NASAL SPRAY is not recommended for use during pregnancy. Discuss all the risks and benefits with your doctor before using this medicine.

Breast-feeding

MIDACIP 1.25 NASAL SPRAY is not recommended for use in nursing mothers. Discuss all the risks and benefits with your doctor before using this medicine.
General warnings

Paradoxical reactions

Paradoxical reactions are reactions to drugs that worsen the symptoms for which the medicine is prescribed. MIDACIP 1.25 NASAL SPRAY should be used with caution due to the increased risk of Paradoxical reactions. These may include excitability, nervousness, hostility, nightmares, sleep disturbances, etc. This risk is especially higher in people with mental disorders. Inform your doctor if you experience any changes in mood and behaviour during treatment with this medicine.

Impaired kidney and liver function

MIDACIP 1.25 NASAL SPRAY is broken down in your liver and excreted through urine. If you have problems with your liver and kidney function, this medicine can further worsen it. Hence avoid taking this medicine if you have such conditions.

Driving or operating machines

MIDACIP 1.25 NASAL SPRAY may cause dizziness or drowsiness. It is advised that you do not perform any activities that require high mental alertness like driving vehicles or operating machines if you experience any of these symptoms during treatment with this medicine.

Use in children

MIDACIP 1.25 NASAL SPRAY is not recommended for use in children less than 12 years of age since the safety and efficacy of use are not clinically established.

Suicidal tendencies

An increased risk of suicidal thoughts or behaviour is observed while taking MIDACIP 1.25 NASAL SPRAY. Hence, close observation for any change in mood or behaviour is necessary while using MIDACIP 1.25 NASAL SPRAY. Take this medicine with caution if you have depression or any other mental health conditions. Report any mood changes to your doctor immediately so that counselling can be done. If the symptoms persist your doctor may advise an alternate medicine.

Missed Dose

Use the missed dose of MIDACIP 1.25 NASAL SPRAY as soon as you remember. If it is time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose of MIDACIP 1.25 NASAL SPRAY.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol during treatment with MIDACIP 1.25 NASAL SPRAY may increase the risk of severe side effects such as confusion, dizziness, nausea, vomiting, weakness, and fainting.
Interaction with Medicine

Amitriptyline

Clozapine

Fluconazole

Disease interactions

Respiratory Depression

Respiratory depression or hypoventilation is a breathing disorder that occurs when there is not enough gas exchange between the lungs and the atmosphere, thus causing slow and ineffective breathing. MIDACIP 1.25 NASAL SPRAY should be taken with extreme caution if you have respiratory depression due to the increased risk of worsening your condition.

Congestive heart failure

Congestive heart failure is a condition in which the heart is unable to pump blood efficiently. MIDACIP 1.25 NASAL SPRAY may worsen your condition; hence take it with caution if you have a history of congestive heart failure.

Depression

Depression is an alteration in a person's mood. MIDACIP 1.25 NASAL SPRAY should be taken with caution if you have depression or any other disorders of the nervous system as it may worsen your condition.

Obesity

Obesity is the condition when you accumulate a harmful amount of fat in your body. MIDACIP 1.25 NASAL SPRAY should be taken with caution in obese people due to the increased risk of severe side effects. Report any unusual symptoms to your doctor immediately. Your doctor may suggest an alternative or adjust the dose accordingly.
Food interactions
Consumption of grapefruit or grapefruit juice is not recommended during treatment with MIDACIP 1.25 NASAL SPRAY due to the increased risk of serious and life-threatening reactions.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Follow all the instructions given by your doctor and administer MIDACIP 1.25 NASAL SPRAY exactly as advised. Do not administer in larger or smaller amounts than prescribed and follow the instructions for use. Seek emergency medical treatment in case of any severe side effects. If the seizure cluster continues after 10 minutes of administration of the first dose of MIDACIP 1.25 NASAL SPRAY, you may use the second dose if have been told to do so by your healthcare provider. If the second dose of MIDACIP 1.25 NASAL SPRAY is used, administer it in the other nostril. Do not give more than 2 doses of MIDACIP 1.25 NASAL SPRAY to treat a seizure cluster. If the seizures do not stop after MIDACIP 1.25 NASAL SPRAY is used, get emergency medical help immediately.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Causes sleepiness

How it works
MIDACIP 1.25 NASAL SPRAY works by decreasing the abnormal electrical activity in your brain.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Benzodiazepines

Schedule

Schedule H1

Nayzilam.com. 2021. Information for Patients | NAYZILAM® (midazolam) nasal spray, CIV. [online] Available at: [Accessed 17 November 2021].

https://www.nayzilam.com/

Drugs, H., 2021. Midazolam Injection: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: [Accessed 16 November 2021].

https://medlineplus.gov/druginfo/meds/a609014.html

Dailymed.nlm.nih.gov. 2021. DailyMed - MIDAZOLAM- midazolam hydrochloride injection. [online] Available at: [Accessed 16 November 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=737361a0-8db1-4d3c-ba5e-44df3f49fa2
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Information on this page was last updated on 9 Mar 2023

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