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Micalan Injection
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Micalan Injection

Manufactured byMylan Pharmaceuticals
ContainsMicafungin
Description
Micalan Injection is an antifungal medicine used for the treatment of fungal infections of the stomach, blood, lungs, and oesophagus. It is also used for the prevention of fungal infections in people undergoing stem cell transplantation. This medicine binds with the fungus cell and kills them. Micalan Injection can cause side effects like nausea, vomiting, cough, loss of appetite, etc. Consult your doctor if these side effects are worsening or getting persistent. Avoid driving vehicles and operating machines after receiving this medicine as it can make you feel drowsy. Micalan Injection is administered by a qualified healthcare professional in a clinic or a hospital. Your dose and duration of the treatment will be decided on the basis of the severity of your condition. Do not stop receiving this medication without consulting your doctor as your symptoms could reoccur. Micalan Injection is not recommended if you are allergic to it. Inform all your current medications and pre-existing medical conditions to your doctor before receiving this medicine. This will help your doctor to adjust your dose for avoiding any side effects. If you are pregnant or breastfeeding, inform your doctor before receiving this medicine.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Micalan Injection

  • Black or tarry stools
  • Cough
  • Fever or chills
  • Increased thirst
  • Loss of appetite
  • Nausea or vomiting
  • Pale skin
  • Shortness of breath
  • Weight gain
  • Drowsiness
  • Bone pain
  • Blurred vision
  • Headache
  • Diarrhoea

Uses of Micalan Injection

What is it prescribed for?

  • Esophageal Candidiasis
  • Candidemia
  • Acute disseminated candidiasis
  • Candida Peritonitis and abscesses
  • Prophylaxis in Hematopoietic Stem Cell Transfer (HSCT) patients
  • Aspergillosis
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for Micalan Injection to show its action is not clinically established.
  • How long do the effects of this medicine last?
    Micalan Injection can remain in your body for 3 to 4 days.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit forming tendency has been reported for Micalan Injection.
  • Can this medicine be taken during pregnancy?
    Micalan Injection is unsafe for use during pregnancy as it can harm your developing foetus. Hence, consult your doctor if you are pregnant.
  • Can this medicine be taken while breast-feeding?
    Due to the lack of relevant safety information, Micalan Injection is not recommended for use while breastfeeding. Consult your doctor if you are breastfeeding.

Allergy

Micalan Injection is not recommended if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.
Warnings for special population

Pregnancy

Micalan Injection is unsafe for use during pregnancy as it can harm your developing foetus. Hence, consult your doctor if you are pregnant.

Breast-feeding

Due to the lack of relevant safety information, Micalan Injection is not recommended for use while breastfeeding. Consult your doctor if you are breastfeeding.
General warnings

Use in children

Micalan Injection is not recommended for use in children less than 4 months of age as the safety and efficacy of use are not clinically established.

Missed Dose

Since Micalan Injection is administered by a qualified healthcare professional in the hospital or clinical setting, the likelihood of missing a dose is very low.

Overdose

Since Micalan Injection is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Sirolimus

Amphotericin B

Disease interactions

Liver Disease

Micalan Injection is broken down and absorbed in the liver. Therefore, a damaged liver will not break it down properly, resulting in toxicity. Your doctor can adjust your dose or replace it with another medicine according to your condition.

Renal Disease

Micalan Injection is filtered by your kidneys. If you have kidney problems, this medicine will not get filtered properly, therefore increasing the risk of toxicity. Your doctor can adjust the dose while monitoring your condition closely or suggest another medicine if required.

Anaemia

Anaemia is a condition in which the number of red blood cells or the haemoglobin concentration within them is lower than normal. Micalan Injection can cause anaemia in some people. Therefore, your doctor will closely monitor your blood cells while you are receiving this medicine.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Micalan Injection is usually administered by a qualified healthcare professional in the hospital or clinical setting. Inform the doctor if you have a known allergy to this medicine. Consult your doctor if you experience any change of colour in your urine or any other side effects.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
Micalan Injection slows the growth of the fungi and kills the fungi that cause the infection.
Legal Status

Approved

Approved

Unknown

Approved

Classification

Category

Echinocandins

Schedule

Schedule H

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https://www.astellas.us/docs/mycamine.pdf>

Accessdata.fda.gov. 2022. [online] Available at: < [Accessed 1 March 2022].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/021506s009lbl.pdf>

Ema.europa.eu. 2022. [online] Available at: < [Accessed 1 March 2022].

https://www.ema.europa.eu/documents/product-information/mycamine-epar-product-information_en.pdf>

Dailymed.nlm.nih.gov. 2022. DailyMed - MYCAMINE- micafungin sodium injection, powder, lyophilized, for solution. [online] Available at: < [Accessed 1 March 2022].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=bc234dd7-5221-4a68-b153-aa0393c75bbf>

Medicines.org.uk. 2022. Mycamine 100 mg powder for concentrate for solution for infusion - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 1 March 2022].

https://www.medicines.org.uk/emc/product/7528/smpc>
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Information on this page was last updated on 6 Jan 2023

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