Micafungin

Description

Micafungin is used for the treatment of fungal infections of the stomach, blood, lungs, and esophagus caused by Candida and Aspergillus species. It is also used for the prevention of Candida and Aspergillus infections in patients undergoing Hematopoietic Stem Cell Transplantation (HSCT).

Side effects

Major & minor side effects for Micafungin

  • Black or tarry stools
  • Cough
  • Fever or chills
  • Increased thirst
  • Loss of appetite
  • Nausea or Vomiting
  • Pale skin
  • Shortness of breath
  • Weight gain
  • Drowsiness
  • Bone pain
  • Blurred vision
  • Headache
  • Diarrhea

Uses of Micafungin

What is it prescribed for?

  • Esophageal Candidiasis
  • Candidemia
  • Acute disseminated candidiasis
  • Candida Peritonitis and abscesses
  • Prophylaxis in Hematopoietic Stem Cell Transfer (HSCT) patients
  • Aspergillosis
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit forming tendency has been reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to Micafungin or any other inactive ingredient present along with it.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.
General warnings

Anaphylaxis and Anaphylactoid reactions

This medicine may cause serious anaphylactic reactions, including shock. Close monitoring of the patients for any signs or symptoms of anaphylactic reactions is recommended. Appropriate corrective measures and/or replacement with a suitable alternative may be necessary based on the clinical condition.

Use in pediatrics

This medicine is not recommended for use in patients less than 4 months of age since the safety and efficacy of use are not clinically established.

Missed Dose

Since this medicine is administered by a qualified healthcare professional in the hospital or clinical setting, the likelihood of missing a dose is very low.

Overdose

Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Sirolimus

Amphotericin B

Disease interactions

Liver Disease

This medicine should be used with caution in patients suffering from liver diseases due to the increased risk of serious adverse effects. Close monitoring of liver function tests is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Renal Disease

This medicine should be used with caution in patients suffering from kidney diseases due to the increased risk of serious adverse effects. Close monitoring of kidney function tests is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Anemia

This medicine should be used with caution in patients suffering from anemia due to the increased risk of worsening of the condition. Close monitoring of hemoglobin levels is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This medicine should only be administered by a qualified healthcare professional. Carefully follow all the instructions given by your doctor. Report to the doctor all your current medicines as well as your medical conditions before receiving this medicine.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine slows the growth of the fungi and kills the fungi that cause the infection.
Legal Status

Approved

Approved

Unknown

Approved

Classification

Category

Echinocandins

Schedule

Schedule H

[Internet]. Astellas.us. 2018 [cited 27 September 2018]. Available from:

https://www.astellas.us/docs/mycamine.pdf

[Internet]. Accessdata.fda.gov. 2018 [cited 27 September 2018]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/021506s009lbl.pdf

[Internet]. Ema.europa.eu. 2018 [cited 27 September 2018]. Available from:

https://www.ema.europa.eu/documents/product-information/mycamine-epar-product-information_en.pdf

[Internet]. India-pharma.gsk.com. 2018 [cited 27 September 2018]. Available from:

https://india-pharma.gsk.com/media/701264/mycamine.pdf

DailyMed - Micafungin sodium injection, powder, lyophilized, for solution [Internet]. Dailymed.nlm.nih.gov. 2018 [cited 27 September 2018]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=bc234dd7-5221-4a68-b153-aa0393c75bbf

Micafungin - DrugBank [Internet]. Drugbank.ca. 2018 [cited 27 September 2018]. Available from:

https://www.drugbank.ca/drugs/DB01141

Mycamine 100mg powder for solution for infusion - Summary of Product Characteristics (SmPC) - (eMC) [Internet]. Medicines.org.uk. 2018 [cited 27 September 2018]. Available from:

https://www.medicines.org.uk/emc/product/7528/smpc

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Information on this page was last updated on 4 Jun 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.