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Mahacef 400 MG Tablet

Manufactured byMankind Pharmaceuticals Ltd.
ContainsCefixime
Description
Mahacef 400 MG Tablet is an antibiotic used to treat bacterial infections affecting the lungs, throat, kidneys, bladder, ureter, and urethra. It is also used to treat a sexually transmitted infection called gonorrhoea. This medicine kills bacteria and prevents the spread of infections. It is not effective against infections caused by viruses or fungi. Mahacef 400 MG Tablet has some common side effects such as diarrhoea, stomach pain, headache, weakness, nausea, and vomiting. Consult your doctor if these symptoms persist or worsen. Avoid any activity that requires concentration if you feel drowsy after taking this medicine. Do not take this medicine if you are allergic to it. Mahacef 400 MG Tablet can be taken with or without food. Take it as directed by your doctor and ensure that you complete the entire course of this medicine. Do not stop taking this medicine on your own, as it may cause re-infection that would be difficult to treat. Contact your doctor if you do not feel better even after completing the course of treatment. Mahacef 400 MG Tablet may not be suitable for everyone. Inform your doctor if you have liver or kidney problems or any other health conditions before taking this medicine. Also, inform your doctor about all your current medications to avoid any undesired effects. If you are pregnant or are breastfeeding, consult your doctor before taking Mahacef 400 MG Tablet.

Side effects

Major & minor side effects for Mahacef 400 MG Tablet

  • Diarrhoea
  • Stomach pain
  • Dark or clay coloured stools
  • Dizziness
  • Acid or sour stomach
  • Excessive air or gas in stomach
  • Heartburn
  • Cough
  • Nausea and Vomiting

Uses of Mahacef 400 MG Tablet

What is it prescribed for?

  • Urinary Tract Infection
  • Gonorrhoea
  • Pharyngitis/Tonsillitis
  • Acute bronchitis
  • Acute Otitis Media
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The time taken for Mahacef 400 MG Tablet to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The time duration for which Mahacef 400 MG Tablet remains active in your body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendency has been reported for Mahacef 400 MG Tablet.
  • Can this medicine be taken during pregnancy?
    Mahacef 400 MG Tablet may be safe to use in pregnancy to treat bacterial infections. Animal studies indicate no risk to the foetus; however, data on human studies are not available. Therefore, use Mahacef 400 MG Tablet only upon your doctor's recommendation.
  • Can this medicine be taken while breast-feeding?
    It is not known if Mahacef 400 MG Tablet passes into the breastmilk. Hence, if you are breastfeeding consult your doctor before taking this medicine.

Allergy

Avoid taking Mahacef 400 MG Tablet if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of your face/tongue/throat), severe dizziness, breathing difficulty, etc.
Warnings for special population

Pregnancy

Mahacef 400 MG Tablet may be safe to use in pregnancy to treat bacterial infections. Animal studies indicate no risk to the foetus; however, data on human studies are not available. Therefore, use Mahacef 400 MG Tablet only upon your doctor's recommendation.

Breast-feeding

It is not known if Mahacef 400 MG Tablet passes into the breastmilk. Hence, if you are breastfeeding consult your doctor before taking this medicine.
General warnings

Diarrhoea

Mahacef 400 MG Tablet may also kill the helpful bacteria in your stomach or intestine. This leads to an overgrowth of the Clostridium difficile bacteria which releases toxins and cause severe diarrhoea. Seek medical help if you experience severe diarrhoea that persists or worsens.

Antibiotic resistance

Antibiotic resistance occurs when bacteria evolve and gain the ability to defeat the antibiotics intended to kill them. Finish your entire course of treatment with Mahacef 400 MG Tablet, even if your condition gets better after a few doses, to avoid antibiotic resistance. Consult your doctor if you still feel unwell after completing your antibiotic course.

Driving or operating machines

Mahacef 400 MG Tablet may cause dizziness, confusion, or fits in some cases. Avoid driving vehicles or operating machines if you experience such symptoms.

Allergic skin reaction

Mahacef 400 MG Tablet is likely to cause severe skin reactions. Seek immediate medical attention if you notice any symptoms such as skin rash, blisters (fluid-filled bumps), or lesions (a part of the skin that has an abnormal growth or appearance).

Liver diseases

Mahacef 400 MG Tablet may increase liver enzyme levels and cause liver damage. Hence, this medicine should be used with caution if you have liver problems. Your doctor may adjust the dose of this medicine based on your clinical condition.

Seizures

Seizure is a condition that occurs due to disturbed nerve cell activity in your brain resulting in abnormal behaviour and loss of consciousness. Mahacef 400 MG Tablet should be used with caution if you have a history of seizures as this medicine may trigger seizures.

Missed Dose

Take the missed dose of Mahacef 400 MG Tablet as soon as you remember. If it is time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Never take more than the prescribed dose. Seek emergency medical attention in case of an overdose with Mahacef 400 MG Tablet.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Furosemide

Amikacin

Ethinyl Estradiol

Warfarin

Cholera Vaccine (live)

Disease interactions

Colitis

Colitis is the swelling of the large intestine. Mahacef 400 MG Tablet can kill the helpful bacteria in your stomach or intestine and lead to diarrhoea. Therefore use this medicine with extreme caution if you have stomach and intestinal problems, particularly colitis, as it may worsen your health condition.

Kidney Disease

Mahacef 400 MG Tablet is filtered by the kidney and excreted through urine. Hence, this medicine should be used with caution if you have kidney problems, as it may increase the risk of kidney damage.
Food interactions
Information not available.
Lab interactions

Coombs test

Coombs' test is done to find certain antibodies (proteins generated by the body's immune system) that attack red blood cells. Inform your doctor or lab technician regarding the use of Mahacef 400 MG Tablet if you are undergoing the Coombs test. A false-positive result may be obtained if this test is performed while taking this medicine.

Urine ketones test

A urine ketone test measures ketone levels in your urine. Inform your doctor or lab technician regarding the use of Mahacef 400 MG Tablet if you are undergoing the urine ketone test. A false-positive result may be obtained if this test is performed while taking this medicine.
Mahacef 400 MG Tablet may be taken with or without food as instructed by your doctor. Avoid taking more or less than the prescribed dose. Finish the entire course of treatment and avoid discontinuing this medicine on your own, even if you feel better after a few doses. Mahacef 400 MG Tablet may kill the helpful bacteria in your stomach and intestine and cause diarrhoea. Consult your doctor if it persists or worsens. Do not give your medicine to others even if their condition appears to be the same as yours.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Mahacef 400 MG Tablet works by preventing the formation of the bacterial cell wall (protective outer covering of the bacteria). This stops the growth and multiplication of bacteria and eventually kills them.
Legal Status

Approved

Approved

Unknown

Approved

Classification

Category

Third generation cephalosporins, Antibiotics

Schedule

Schedule H

Medicines.org.uk. 2021. Suprax 200 Mg Tablets - Summary Of Product Characteristics (Smpc) - (Emc). [online] Available at: < [Accessed 4 January 2021].

https://www.medicines.org.uk/emc/product/5534>

Lupinpharmaceuticals.com. 2021. [online] Available at: < [Accessed 4 January 2021].

http://www.lupinpharmaceuticals.com/pdf/09/SUPRAX%20Common%20PI%20.pdf>

Products.sanofi.ca. 2021. [online] Available at: < [Accessed 4 January 2021].

http://products.sanofi.ca/en/suprax.pdf>

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 4 January 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/203195s000lbl.pdf>
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Information on this page was last updated on 16 Feb 2022

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