Cefixime

Description

Cefixime is a cephalosporin antibiotic. It is used to treat bacterial infections in many different parts of the body. Cefixime kills or stops the growth of bacteria causing the infection. It is not effective against infections caused by viruses. Common side effects of this medicine are diarrhoea, stomach pain, headache, weakness, nausea, and vomiting. Do not take this medicine if you are previously allergic to it. Cefixime is available on prescription as a capsule, tablet, chewable, powder for suspension and syrup. Due to its once-daily dosing regime, it has become a frequent choice for all doctors and patients. In children, this medicine may also be taken two times a day. Once an antibiotic is started, it is always recommended to finish the entire course of treatment. Cefixime should only be used to treat or prevent infections that are caused by bacteria. Taking an antibiotic when it is not required can make it less effective for future infections. You can take Cefixime with or without food. For the ease of remembering, take this medicine around the same time every day.

Side effects

Major & minor side effects for Cefixime

  • Stomach pain
  • Dark or clay coloured stools
  • Dizziness
  • Excessive air or gas in stomach
  • Heartburn
  • Chest pain
  • Headache
  • Fever
  • Diarrhoea
  • Acid or sour stomach

Uses of Cefixime

What is it prescribed for?

  • Urinary tract infection
  • Acute bronchitis
  • Pharyngitis/Tonsilitis
  • Acute bacterial otitis media
  • Gonorrhoea
Read More
Concerns

Commonly asked questions

  • Onset of action
    You will start to feel better in 3 to 5 days after taking cefixime. But finish your entire course of treatment, even if your condition gets better.
  • Duration of effect
    The duration of action for cefixime is not clinically determined.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendency has been reported for Cefixime.
  • Usage in pregnancy?
    Cefixime is generally safe in pregnancy to treat bacterial infections. It is not known to cause birth defects when taken by pregnant women. Hence it is acceptable for use upon your doctor's recommendation.
  • Usage while breast-feeding?
    Cefixime is safe to use during breastfeeding. It is not known to be harmful to breastfeeding women. Hence it is acceptable for use upon your doctor's recommendation. Baby should be observed for symptoms such as diarrhoea and yeast infection.

Allergy

Avoid taking Cefixime if you are previously allergic to it. Some patients may get allergic reactions to this medicine. Seek immediate medical attention if you notice any symptoms of allergic reactions such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulties, etc.
Warnings for special population

Pregnancy

Cefixime is generally safe in pregnancy to treat bacterial infections. It is not known to cause birth defects when taken by pregnant women. Hence it is acceptable for use upon your doctor's recommendation.

Breast-feeding

Cefixime is safe to use during breastfeeding. It is not known to be harmful to breastfeeding women. Hence it is acceptable for use upon your doctor's recommendation. Baby should be observed for symptoms such as diarrhoea and yeast infection.
General warnings

Allergic skin reaction

Cefixime is likely to cause allergic skin reactions in some people. Seek immediate medical attention if you notice any symptoms such as skin rash, or severe itching/swelling, especially on the face.

Antibiotic resistance

Finish your entire course of treatment with Cefixime, even if the condition gets better to avoid antibiotic resistance (the bacteria may become resistant to antibiotics). If you still feel unwell after completing your antibiotic course, make an appointment to consult your doctor.

Diarrhoea

Cefixime can cause diarrhoea because it may also kill the helpful bacteria in your stomach or intestine. Get emergency medical help if you experience severe diarrhoea that is watery or bloody. Call your pharmacist/doctor before taking anti-diarrhoeal medication. Your doctor may prescribe cefixime lactic acid bacillus tablets in case of severe diarrhoea.

Driving or operating machinery

Cefixime may cause dizziness, confusion, or fits in some people. Do not drive a vehicle or operate machinery after taking this medicine.

Liver diseases

Cefixime may increase liver enzyme levels and cause liver swelling. Patients with liver diseases need special consideration while taking Cefixime due to the risk of liver damage. Dose adjustment should be done based on the clinical condition.

Seizures

Use Cefixime with caution in patients with seizures or fits because it can trigger the condition. Seizure medicines should be continued in patients with a known seizure disorder. Dose adjustment for Cefixime might be required in some patients.

Missed Dose

Try not to skip a dose of Cefixime. And if a dose is skipped, do not add it up to the next dose.

Overdose

Seek emergency medical attention in case of an overdose with Cefixime.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Amikacin

Warfarin

Ethinyl Estradiol

Cholera Vaccine

Furosemide

Disease interactions

Colitis

Cefixime can kill the helpful bacteria in your stomach or intestine and leads to diarrhoea. Therefore use Cefixime with extreme caution in patients with gastrointestinal (mouth to anus) diseases, particularly colitis (swelling of the inner lining of the colon), since it may worsen the patient's condition.

Kidney disease

Cefixime is filtered by the kidney and moved out of the body through urine. Patients with kidney diseases need special consideration while taking Cefixime due to the risk of kidney damage. Dose adjustment should be done based on the clinical condition.
Food interactions
Information not available.
Lab interactions

Coombs test

A false-positive result may be obtained if this test is performed while taking Cefixime.

Urine ketones test

Cefixime may cause false-positive reactions for ketones in the urine tests using nitroprusside.
Take Cefixime with or without food. Never take more than the prescribed dose. Take this medicine at around the same time daily. Do not give your medicine to other people even if their condition appears to be the same as yours.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Cefixime works by preventing the formation of bacterial cell walls. This helps in stopping the growth and multiplication of the microorganism, eventually killing it.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Third generation cephalosporins, Antibiotics

Schedule

Schedule H

Lupin.com. 2021. [online] Available at: < [Accessed 4 January 2021].

https://www.lupin.com/US/pdf/09/SUPRAX%20Common%20PI%20.pdf>

Dailymed.nlm.nih.gov. 2021. Dailymed - SUPRAX- Cefixime Tabletsuprax- Cefixime Capsulesuprax- Cefixime Tablet, Chewablesuprax- Cefixime Powder, For Suspension. [online] Available at: < [Accessed 4 January 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=d0fd45bd-7d52-4fa6-a5f7-f46d5651ffa2>

Medicines.org.uk. 2021. Suprax 200 Mg Tablets - Summary Of Product Characteristics (Smpc) - (Emc). [online] Available at: < [Accessed 4 January 2021].

https://www.medicines.org.uk/emc/product/5534>

Drugs, H., 2021. Cefixime: Medlineplus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 4 January 2021].

https://medlineplus.gov/druginfo/meds/a690007.html>

Go.drugbank.com. 2021. Cefixime | Drugbank Online. [online] Available at: < [Accessed 4 January 2021].

https://go.drugbank.com/drugs/DB00671>

Pubchem.ncbi.nlm.nih.gov. 2021. Cefixime. [online] Available at: < [Accessed 4 January 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Cefixime>

How will this medicine affect me?

Consult top doctors online and get an answer now
Consult now
Consult now

Looking for a doctor?

Book an appointment with the top doctors near you
Book now
Book now
Something doesn’t feel right?
Report an error

Information on this page was last updated on 8 Feb 2021

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.