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Esofine 40 MG Tablet
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Esofine 40 MG Tablet

Manufactured byMacleods Pharmaceuticals Pvt. Ltd.
ContainsEsomeprazole
Description
Esofine 40 MG Tablet is an anti-ulcer medicine. It is used to treat conditions where the stomach produces too much acid. Stomach and duodenal ulcers, gastroesophageal reflux disease (a condition in which the stomach acid flows back into your food pipe), and Zollinger-Ellison syndrome are certain problems caused by high levels of stomach acid. It relieves stress ulcers (sores in the stomach and intestine that may occur due to illness, infections, etc.) and also acidity due to the intake of painkillers. Esofine 40 MG Tablet interferes with the final step of acid release in the stomach. Thus, acidity in the stomach is decreased and the ulcer healing process is fastened. Common side effects of Esofine 40 MG Tablet are nausea, vomiting, headache, stomach pain, diarrhoea, and dizziness. Esofine 40 MG Tablet has to be taken one hour before food. Avoid spicy and fatty foods, alcohol, and reduce caffeinated drinks or beverages such as coffee, tea, and cola while using this medicine. Esofine 40 MG Tablet is not recommended for use if you are allergic to it. Inform your doctor if you have liver or kidney problems, or any other health condition. Report all the medicines that you are taking to your doctor as they can interact with this medicine and reduce its effectiveness. If you are pregnant or are breastfeeding, consult your doctor before taking this medicine.
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Side effectsConcernsUsageRelated products

Substitutes

List of substitutes for Esofine 40 MG Tablet

Esomac 40 MG Tablet
Cipla Ltd.
Esoz 40 MG Tablet
Glenmark Pharmaceuticals Ltd.
Omipure Fast 40 MG Tablet
Mankind Pharmaceuticals Ltd.
Raciper Sf 40 MG Tablet
Ranbaxy Laboratories Ltd.
Somifiz 40 MG Tablet
Mankind Pharmaceuticals Ltd.

Side effects

Major & minor side effects for Esofine 40 MG Tablet

  • Headache
  • Nausea or vomiting
  • Excessive gas in stomach
  • Stomach discomfort
  • Skin rash
  • Difficulty in breathing
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Irregular heartbeat
  • Diarrhoea
  • Unusual tiredness and weakness
  • Decreased appetite
  • Dizziness

Uses of Esofine 40 MG Tablet

What is it prescribed for?

  • Erosive Esophagitis
  • Gastroesophagal Reflux Disease
  • Zollinger-Ellison Syndrome
  • Gastric and duodenal ulcers
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    Esofine 40 MG Tablet starts its action within an hour of taking it.
  • How long do the effects of this medicine last?
    Esofine 40 MG Tablet may remain in your body for approximately 9 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Esofine 40 MG Tablet.
  • Can this medicine be taken during pregnancy?
    Esofine 40 MG Tablet is not recommended during pregnancy as not enough studies are done to understand its safety. Consult your doctor before taking this medicine if you are pregnant.
  • Can this medicine be taken while breast-feeding?
    It is not known if Esofine 40 MG Tablet passes into breastmilk. Therefore, if you are breastfeeding, consult your doctor to understand the risks and benefits associated with this medicine.

Allergy

Avoid taking Esofine 40 MG Tablet if you are allergic to it. Allergic reactions are very rare to this medicine. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling of the face/tongue/throat), breathing difficulty, etc.
Warnings for special population

Pregnancy

Esofine 40 MG Tablet is not recommended during pregnancy as not enough studies are done to understand its safety. Consult your doctor before taking this medicine if you are pregnant.

Breast-feeding

It is not known if Esofine 40 MG Tablet passes into breastmilk. Therefore, if you are breastfeeding, consult your doctor to understand the risks and benefits associated with this medicine.
General warnings

Hypomagnesaemia

Long-term use of Esofine 40 MG Tablet may result in hypomagnesaemia (low magnesium levels in your blood) due to excess excretion of it through urine. Inform your doctor if you experience symptoms such as dizziness, irregular heartbeat, shivering, muscle pain, seizures (fits). Your doctor may monitor your magnesium levels at regular intervals during treatment with this medicine.

Lupus erythematosus

Lupus erythematosus is an autoimmune disorder that affects the skin, kidneys, brain, joints, and other organs. It occurs when the immune system of the body attacks its own tissues. Lupus may occur or get worse while you are taking Esofine 40 MG Tablet. Inform your doctor immediately if you experience tiredness, painful joints, rashes, or lesions on the skin during treatment with this medicine.

Vitamin B12 deficiency

Long-term treatment with Esofine 40 MG Tablet may decrease the absorption of Vitamin B12 in your body. Your doctor may prescribe vitamin B12 supplements if this medicine is used for a longer time.

Driving or operating machines

Esofine 40 MG Tablet may cause sleepiness or dizziness. Hence, avoid performing activities such as driving vehicles or operating machines if you experience such symptoms.

Atrophic gastritis

Long-term use of Esofine 40 MG Tablet may cause atrophic gastritis (swelling in the lining of the stomach). Hence, use this medicine only for the prescribed duration.

Missed Dose

If you forget to take Esofine 40 MG Tablet, take it as soon as you remember. However, if it is time for the next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Never take more than the prescribed dose. Seek emergency medical attention in case of an overdose of Esofine 40 MG Tablet.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Clopidogrel

Methotrexate

Warfarin

Nelfinavir

Digoxin

Fluconazole

Disease interactions

Liver Disease

Esofine 40 MG Tablet should be used with caution if you have liver problems. Impaired liver function may lead to an increase in the levels of unused medicine in your blood. Your doctor may adjust your dose or suggest another medicine in such cases.

Osteoporosis

Osteoporosis is a condition in which bones become weak and fragile (may break from a fall). Long-term use of Esofine 40 MG Tablet can reduce bone density (thinning of bones). Hence, this medicine should be used with caution if you have osteoporosis. Your doctor may recommend vitamin D and calcium supplements if you have such conditions.

Colitis

Esofine 40 MG Tablet may cause diarrhoea. Take this medicine with extreme caution if you have stomach and intestine problems, particularly colitis (swelling of the inner lining of the colon), as it may cause severe diarrhoea.
Food interactions
Take Esofine 40 MG Tablet at least 1 hour before meals as food may reduce the absorption of the medicine in your body.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Esofine 40 MG Tablet as instructed by your doctor. Do not break, crush or chew the capsule. Take Esofine 40 MG Tablet for the recommended duration. Avoid taking more or less than the prescribed dose. Avoid spicy and fatty foods, alcohol, and caffeinated drinks or beverages (such as coffee, tea, and cola) while taking this medicine. Consult your doctor if your condition is not improving after a few days or if your symptoms are getting worse.
Miscelleneous

To be taken before food

To be taken as instructed by doctor

May cause sleepiness

How it works
Esofine 40 MG Tablet reduces the production of acid in the stomach. It stops the action of the proton pumps that are found on cells that line the stomach, which decreases stomach acid production.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Proton pump inhibitors, Anti-Ulcer Agents

Schedule

Schedule H

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https://pubchem.ncbi.nlm.nih.gov/compound/Esomeprazole>

Drugs, H., 2021. Esomeprazole: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 2 March 2021].

https://medlineplus.gov/druginfo/meds/a699054.html>

Medicines.org.uk. 2021. Esomeprazole 20 mg gastro-resistant capsules, hard - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 2 March 2021].

https://www.medicines.org.uk/emc/product/12019/smpc>

Dailymed.nlm.nih.gov. 2021. DailyMed - ESOMEPRAZOLE capsule. [online] Available at: < [Accessed 2 March 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7a7b80f1-fd8a-a78f-e053-2991aa0a7098>

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 2 March 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/022101s014021957s017021153s050lbl.pdf>

Medicalinformation.astrazeneca-us.com. 2021. NEXIUM® (esomeprazole magnesium) Prescribing Information | AZ Medical Information. [online] Available at: < [Accessed 2 March 2021].

https://medicalinformation.astrazeneca-us.com/home/prescribing-information/nexium-pi.html>
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Information on this page was last updated on 12 Nov 2021

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