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Epsolin 50 MG Tablet

Manufactured byZydus Cadila
ContainsPhenytoin
Description

Epsolin 50 MG Tablet is an anticonvulsant used for the treatment of tonic-clonic (grand mal) and psychomotor (temporal lobe) seizures (a brain disorder characterized by uncontrolled jerking movements and loss of consciousness). It is also used to control and/or prevent seizures that may occur during or after brain surgeries or severe head injuries.

Side effects

Major & minor side effects for Epsolin 50 MG Tablet

  • Decreased coordination
  • Nervousness
  • Unsteadiness
  • Shaking of hands or feet
  • Unusual facial expressions
  • Trouble sleeping
  • Uncontrolled eye movements
  • Yellow colored eyes or skin
  • Skin rash
  • Headache

Uses of Epsolin 50 MG Tablet

What is it prescribed for?

  • Seizures
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The peak effect of this medicine can be observed in 1.5 to 3 hours after administration.
  • How long do the effects of this medicine last?
    The effect of this medicine lasts for an average duration of 2 to 3 days.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit forming tendency has been reported
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. If the medicine is used, the infant should be monitored closely for any adverse effects.

Allergy

This medicine is not recommended for use in patients with a known allergy to phenytoin or any other inactive ingredients present along with the formulation.

Delavirdine

This medicine is not recommended for use in patients receiving delavirdine, an antiviral medicine used for the treatment of an HIV infection, since it may worsen the patient's condition.

Heart rhythm disorders

This medicine is not recommended for use in patients suffering from heart rhythm disorders such as sinus bradycardia, sino-atrial block, second or third-degree AV-block, Adams-Stokes syndrome, etc. due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. If the medicine is used, the infant should be monitored closely for any adverse effects.
General warnings

Withdrawal symptoms

Abrupt discontinuation of this medicine may increase the risk of severe adverse effects, especially if you have been using a high dose for a long duration. A gradual dose reduction is recommended to avoid these reactions. Do not stop the use of this medicine without consulting your doctor.

Suicidal thoughts

This medicine may increase the risk of suicidal thoughts upon treatment. Therefore, it should be used with caution, especially in patients suffering from depression or suicidal tendencies. Close monitoring of mood and behavior is necessary for such patients. Appropriate caregiver and patient counseling, dose adjustments, or replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Skin reactions

This medicine should be used with caution since it may cause skin reactions like Stevens-Johnson syndrome, toxic epidermal necrolysis, Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS), etc. in some patients. The treatment should be discontinued if any symptoms of a skin rash appear.

Effects on bone

This medicine is known to decrease bone density and may increase the risk of osteoporosis and osteomalacia. Inform the doctor if you have any bone disorder. Close monitoring of Vitamin-D levels and radiological findings is necessary while receiving this medicine. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Megaloblastic anemia

This medicine should be used with caution in patients suffering from megaloblastic anemia or folate deficiency due to the increased risk of worsening of the patient's condition. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

Driving or operating machinery

This medicine may cause dizziness, blurred vision, or drowsiness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any of these symptoms.

Blood cell count

This medicine may cause neutropenia, anemia, and aplastic anemia. Frequent monitoring of blood cell count is necessary. Any signs of low blood count should be reported to the doctor. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Missed Dose

Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Voriconazole

Warfarin

Ethinyl Estradiol

Metaxalone

Disease interactions

Porphyria

This medicine should be used with caution patients with porphyria due to the increased risk of worsening of the patient's condition. Close monitoring of the clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Arrhythmias

This medicine should be used with caution in patients suffering from cardiovascular diseases and conduction abnormalities due to the increased risk of worsening of the patient's condition. Close monitoring of the heart function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Diabetes Mellitus

This medicine should be used with caution in patients suffering from diabetes mellitus due to the increased risk of elevated blood sugar levels. Close monitoring of blood sugar levels, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

Liver Disease

This medicine should be used with caution in patients suffering from liver impairment due to the increased risk of severe adverse effects. Close monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Kidney Disease

This medicine should be used with caution in patients suffering from kidney impairment due to the increased risk of severe adverse effects. Close monitoring of kidney function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine with or without food. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesired side effects. Ensure that the course of treatment is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by decreasing the abnormal electrical activity in the brain by inhibiting the repetitive firing of neurons.
Legal Status

Approved

Unknown

Approved

Approved

Classification

Category

Hydantoin anticonvulsants

Schedule

Schedule H

Phenytoin: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2020 [cited 8 May 2020]. Available from:

https://medlineplus.gov/druginfo/meds/a682022.html

[Internet]. Medicines.org.uk. 2020 [cited 8 May 2020]. Available from:

https://www.medicines.org.uk/emc/files/pil.4225.pdf

Phenytoin - DrugBank [Internet]. Drugbank.ca. 2020 [cited 8 May 2020]. Available from:

https://www.drugbank.ca/drugs/DB00252

Phenytoin [Internet]. Pubchem.ncbi.nlm.nih.gov. 2020 [cited 8 May 2020]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/Phenytoin
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Information on this page was last updated on 19 May 2020

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We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.