E Mal 150 mg Injection

Manufactured byThemis Medicare Ltd.
ContainsArteether
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Description

E Mal 150 mg Injection is an effective anti-malarial medicine. It is used to treat severe malaria caused by Plasmodium falciparum strains when other medicines are not effective.

Side effects

Major & minor side effects for E Mal 150 mg Injection

  • Headache
  • Nausea or Vomiting
  • Persistent cough
  • Dizziness
  • Body pain
  • Pain at the injection site
  • Stomach discomfort and pain
  • Chills and rigor
  • Watery diarrhea
  • Unusual tiredness and weakness
  • Low WBC and Platelet count
  • Swelling of the liver

Uses of E Mal 150 mg Injection

What is it prescribed for?

  • Acute malaria
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Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed within 10-12 hours of administration.
  • Duration of effect
    The time duration for which this medicine remains effective in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit forming tendencies were reported.
  • Usage in pregnancy?
    Use of this medicine in pregnant women is not recommended unless absolutely necessary. The effect of this medicine on pregnancy is not clearly established and hence should be used only in life-threatening situations.
  • Usage while breast-feeding?
    Use of this medicine while breastfeeding is not recommended unless necessary. Your doctor will determine whether or not to use this medicine.

Allergy

This medicine is not recommended for use if you have a known history of allergy to Arteether or any other Artemisinin derivatives.
Warnings for special population

Pregnancy

Use of this medicine in pregnant women is not recommended unless absolutely necessary. The effect of this medicine on pregnancy is not clearly established and hence should be used only in life-threatening situations.

Breast-feeding

Use of this medicine while breastfeeding is not recommended unless necessary. Your doctor will determine whether or not to use this medicine.
General warnings

Severe malaria

This medicine should be used to treat malaria only when it is severe and other medicines like quinine are proving to be ineffective.

Medicine induced fever

Use of this medicine can cause fever as a side effect.

Liver/kidney impairment

This medicine should be used with caution in patients having an impaired liver/kidney function. If the impairment is very severe, then the use of this medicine should be avoided.

Heart disease

This medicine should be used with caution in patients suffering from a pre-existing condition of the heart.

Drug resistance

It is strongly recommended to take this medicine for the entire prescribed duration even when symptoms resolve or improve. Failure to do so might result in parasitic resistance to the drug and treatment of further infection with this medicine would become difficult.

Missed Dose

Contact your doctor immediately if you miss a scheduled dose of this medicine.

Overdose

Contact your doctor immediately if an overdose with this medicine is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Quetiapine

Mefloquine

Disease interactions

Liver Disease

This medicine should be administered with caution in patients having an impaired liver function. Appropriate diagnostic tests must be performed before determining the dose regimen. Suitable dose adjustment and frequent monitoring may be needed to ensure safe and effective use.

Kidney disease

This medicine should be administered with caution in patients having an impaired kidney function. Suitable dose adjustment and frequent monitoring may be needed to ensure safe and effective use.
Food interactions
Information not available.
Lab interactions
Information not available.
Take E Mal 150 mg Injection as prescribed by the doctor. Do not take more or less than the recommended quantity and duration. It is advised to take this medicine under the supervision of a doctor or a healthcare professional.
Miscelleneous

To be taken after food

To be taken as instructed by doctor

Effect on sleep is not established

How it works
This medicine works by interfering with certain vital functions in the cell of the malarial parasite present in the blood.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Antimalarial agents

Schedule

Schedule H

arteether: Indication, Dosage, Side Effect, Precaution | CIMS India [Internet]. Mims.com. 2017 [cited 8 June 2017]. Available from:

http://www.mims.com/india/drug/info/arteether/?type=full&mtype=generic#Indications

Artemotil | C17H28O5 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 8 June 2017]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/3000469#section=Top

Artemisinin: mechanisms of action, resistance and toxicity. - PubMed - NCBI [Internet]. Ncbi.nlm.nih.gov. 2017 [cited 8 June 2017]. Available from:

https://www.ncbi.nlm.nih.gov/pubmed/12435450

Dose-finding and efficacy study for i.m. artemotil (beta-arteether) and comparison with i.m. artemether in acute uncomplicated P. falciparum malaria. - PubMed - NCBI [Internet]. Ncbi.nlm.nih.gov. 2017 [cited 8 June 2017]. Available from:

https://www.ncbi.nlm.nih.gov/pubmed/11994055
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