Warnings for special population
This medicine should be used by pregnant women only when the potential benefits outweigh the risks involved. Consult your doctor before using this medicine.
This medicine is not recommended for use by breastfeeding women. It is recommended to discontinue breastfeeding before starting the treatment with this medicine. Consult your doctor before using this medicine.
Suicidal thinking and behaviour
Use of this medicine may cause suicidal thought and change the behavior of the user. This risk is increasingly high in young patients. It is recommended to screen the patient for such behavior before starting the treatment. Any change in behavior and thought process after taking this medicine should be reported to the doctor immediately.
Use of this medicine with other medicines to treat depression may cause nausea, agitation, seizures and hallucinations (symptoms of serotonin syndrome)
Neuroleptic malignant syndrome
Use of this medicine may cause Neuroleptic malignant syndrome characterized by high fever, muscle stiffness, extreme changes in blood pressure, excessive sweating and salivation. The use of this medicine should be stopped as soon as these side effects are experienced.
Use of this medicine is associated with a sharp increase in blood pressure levels. It is recommended to control hypertension using appropriate medicines before starting the treatment with desvenlafaxine.
Use of this medicine may cause unusual bleeding and bruising and hence should be used with caution in patients suffering from bleeding disorders. Use of medicines that are known to cause gastrointestinal bleeding, (example: aspirin, paracetamol, ibuprofen etc), should be avoided while taking desvenlafaxine.
This medicine should be used with caution in patients suffering from angle closure glaucoma. The symptoms of this disease may worsen upon using desvenlafaxine and hence caution is advised.
Use of this medicine may cause seizures and hence should be used with caution in patients suffering from epilepsy.
Use of this medicine may cause agitation and aggressive behavior in some patients. The patient should be screened for bipolar disorder before starting the treatment course with this medicine.
This medicine should be used with caution in patients suffering from a heart or blood vessel disorder.
This medicine may decrease the sodium levels in the body and hence should be used with caution in patients taking diuretic medicines.
Use of this medicine has been associated with an increase in the incidence of bone fractures. Report any incidence of bone pain to the doctor while taking desvenlafaxine.
Drowsiness and cognitive impairment
Use of this medicine has been associated with drowsiness and impairment of cognition. It is advised to refrain from driving vehicles or operating heavy machinery while taking this medicine.
Use of this medicine may cause sexual dysfunction. These dysfunctions may include a decrease in libido, erectile disorders, or unusual orgasm.
Use of this medicine should not be discontinued abruptly. It is advised to gradually reduce the dose of this medicine.
Monoamine oxidase inhibitor drugs
This medicine should be used at least 14 days after stopping the use of MOAI drugs. Use of desvenlafaxine should stop at least 7 days before using the other medicine.
This medicine is not recommended for use in patients aged below 18 years.
Use in elderly
This medicine should be used with caution in elderly patients as the risk of adverse effects is significantly high.