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Zyven 50 MG Tablet

Manufactured byZydus Cadila
Description
Zyven 50 MG Tablet is an effective medicine to treat depression which is a mood disorder characterized by extreme sadness, irritability, and loss of interest in activities.

Side effects

Major & minor side effects for Zyven 50 MG Tablet

  • Suicidal thinking and behaviour
  • Irregular heartbeat
  • Shaking of the hands or feet
  • Dizziness when getting up suddenly from a sitting position
  • Chills or cold sweats
  • Blurred vision
  • Nausea and Vomiting
  • Dry mouth
  • Constipation
  • Muscle stiffness
  • Decrease in libido
  • Difficulty in passing urine
  • Rapid weight gain/loss
  • Ringing or buzzing in the ears

Uses of Zyven 50 MG Tablet

What is it prescribed for?

  • Depression
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of severe side effects such as dizziness, difficulty in concentration, impaired judgment, etc. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
  • Is this a habit forming medicine?
    No habit forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known history of allergy to desvenlafaxine or any other inactive ingredients present in the formulation.

Monoamine oxidase inhibitors (MAOI)

This medicine is not recommended for use while an MAOI (Rasagiline/Selegiline, etc.) is being consumed. This medicine should be consumed at least 14 days after stopping the use of MAOI medicines.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Suicidal thoughts

This medicine may increase the risk of suicidal thoughts in some patients. Patients should be monitored closely for any changes in behavior or mood. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Urinary tract obstruction

This medicine should be used with caution in patients with urinary tract obstruction since it may worsen the patient's condition. Close monitoring of the clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Neuroleptic malignant syndrome

This medicine should be used with extreme caution in patients with a known history of a neuroleptic malignant syndrome (NMS) due to the increased risk of worsening of the patient's condition. Close monitoring of the clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Bleeding disorders

This medicine should be used with extreme caution in patients suffering from bleeding disorders due to the increased risk of worsening of the patient's condition. Close monitoring of the clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Manic episodes

The use of this medicine may cause agitation and aggressive behavior in some patients. The patient should be screened for bipolar disorder before starting the treatment course with this medicine.

Heart diseases

This medicine should be used with caution in patients suffering from heart diseases due to the increased risk of severe adverse effects. Close monitoring of heart function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition. It is not recommended for use in patients with severe heart diseases.

Hyponatremia

This medicine should be used with caution in patients having low sodium levels in the body. It is recommended to initiate treatment with this medicine only after the sodium deficit is corrected. Close monitoring of sodium levels, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Bone fractures

The use of this medicine has been associated with an increase in the incidence of bone fractures. Report any incidence of bone pain to the doctor immediately. Close monitoring of the clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Sexual dysfunction

The use of this medicine may cause sexual dysfunction. These dysfunctions may include a decrease in libido, erectile disorders, or unusual orgasm.

Withdrawal symptoms

The use of this medicine should not be discontinued abruptly since some patients may suffer from withdrawal symptoms such as a headache, anxiety, etc. Your doctor may suggest an appropriate titration regimen prior to stopping treatment with this medicine.

Use in children

This medicine is not recommended for use in children below 18 years of age since the safety and efficacy of use are not clinically established.

Use in elderly population

This medicine should be used with extreme caution in the elderly population due to the increased risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Driving or operating machinery

The use of this medicine may cause blurred vision, drowsiness, or dizziness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any of these symptoms.

Missed Dose

Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of severe side effects such as dizziness, difficulty in concentration, impaired judgment, etc. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Linezolid

Lithium

Sertraline

Warfarin

Aspirin

Methylene blue

Sumatriptan

Disease interactions

Kidney Disease

This medicine should be used with caution in patients suffering from kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Glaucoma

This medicine should be used with caution in patients with glaucoma due to the increase in the fluid pressure in the eye. Inform the doctor if you have any history of eye disorder. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Hypertension

This medicine should be used with caution in patients suffering from hypertension (Increased blood pressure) due to the increased risk of worsening of the patient's condition. Report any unusual symptoms to the doctor immediately. Close monitoring of blood pressure levels, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

Liver Disease

This medicine should be used with caution in patients suffering from liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Seizure disorders

This medicine should be used with caution in patients with seizure disorders since it may worsen the patient's condition. Close monitoring of the clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.
Food interactions
Information not available.
Lab interactions

Test for Phencyclidine (PCP) and amphetamine

Report the use of this medicine to the doctor if you are taking a screening test for Phencyclidine (PCP) or amphetamine. The use of this medicine may interfere with the test results.
Take this medicine exactly advised by your doctor. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable effects. Do not stop taking this medicine before completion of the course/without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Causes sleepiness

How it works
This medicine works by affecting the levels of serotonin and norepinephrine in the brain by preventing the reuptake and thus increasing their activity.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Serotonin-norepinephrine reuptake inhibitors

Schedule

Schedule H

[Internet]. Medlineplus.gov. 2020 [cited 18 March 2020]. Available from:

https://medlineplus.gov/druginfo/meds/a608022.html

Desvenlafaxine - DrugBank [Internet]. Drugbank.ca. 2020 [cited 18 March 2020]. Available from:

https://www.drugbank.ca/drugs/DB06700

Desvenlafaxine [Internet]. Pubchem.ncbi.nlm.nih.gov. 2020 [cited 18 March 2020]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/Desvenlafaxine
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Information on this page was last updated on 31 Mar 2020

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