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Dralgeen 20 mg Injection

Manufactured byBharat Serums & Vaccines Ltd.
ContainsHydralazine
Description
Dralgeen 20 mg Injection is an antihypertensive medicine, which is used to control high blood pressure. It may also be used for the treatment of emergency hypertensive conditions. This medicine is not recommended for use in children less than 18 years of age. Parenteral therapy should only be used when the patient is unable to take the medicine orally.

Substitutes

List of substitutes for Dralgeen 20 mg Injection

Hydralazine Hydrochloride 20 mg Injection
Bharat Serums & Vaccines Ltd.

Side effects

Major & minor side effects for Dralgeen 20 mg Injection

  • Nausea
  • Fast/irregular heart beat
  • Blurred vision
  • Skin rash/itching
  • Dizziness
  • Swelling of feet and lower legs
  • Loss of appetite
  • Weight loss

Uses of Dralgeen 20 mg Injection

What is it prescribed for?

  • Hypertension
  • Hypertensive Emergency
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed within 10-80 minutes after intravenous administration.
  • How long do the effects of this medicine last?
    The effect of this medicine lasts for an average duration of 1-4 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No-habit forming tendency has been reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to hydralazine, or any other inactive ingredients present in the formulation.

Coronary artery disease

This medicine is not recommended for use in patients with a known history of coronary heart disease,due to the increased risk of worsening of the patient's condition.

Rheumatic heart disease

This medicine is not recommended for use in patients with a known history of rheumatic heart disease, due to the increased risk of worsening of the patient's condition.

Porphyria

This medicine is not recommended for use in patients with a known history of porphyria, due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
General warnings

Systemic lupus erythematosus

Prolonged use of this medicine may increase the risk of systemic lupus erythematosus. The medicine should be discontinued under the doctor's supervision if the patient experiences any unusual reactions.

Bone marrow suppression

This medicine should be used in patients with blood-related disorders, since it may decrease the blood cell count of hemoglobin, red cell count, agranulocytosis, leukopenia, and purpura have been reported. Clinical monitoring blood counts should be considered for those patients at higher risk.

Use in children

This medicine is not recommended for use in patients less than 18 years of age since the safety and efficacy of use are not clinically established.

Driving and operating machinery

This medicine may cause symptoms such as dizziness, visual disturbances, fainting, weakness, etc. in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during or immediately after receiving this medicine.

Missed Dose

Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low.

Overdose

Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Corticosteroids

Aspirin

Tizanidine

Alprazolam

Diclofenac

Disease interactions

Systemic Lupus Erythematosus

The prolonged use of this medicine may increase the risk of systemic lupus erythematosus. The medicine should be discontinued under the doctor's supervision if the patient experiences any unusual reactions.

Liver Disease

This medicine should be used with caution in patients with liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Kidney Disease

This medicine should be used with caution in patients with kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Cerebral vasculopathy

This medicine should be used with caution in patients with cerebral vasculopathy due to the increased risk of severe adverse effects. Close monitoring of the clinical conditions is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by relaxing blood vessels which increases the supply of blood and oxygen to the heart.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Vasodilators

Schedule

Schedule H

Hydralazine - DrugBank [Internet]. Drugbank.ca. 2020 [cited 20 May 2020]. Available from:

https://www.drugbank.ca/drugs/DB01275

HYDRALAZINE HYDROCHLORIDE INJECTION, USP 20 mg/mL [Internet]. Dailymed.nlm.nih.gov. 2020 [cited 20 May 2020]. Available from:

https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=2aa312d6-4618-45ad-9a43-b3abd130f8dc&type=display

[Internet]. Medsafe.govt.nz. 2020 [cited 20 May 2020]. Available from:

https://www.medsafe.govt.nz/Consumers/cmi/a/apresoline.pdf

[Internet]. Medicines.org.uk. 2020 [cited 20 May 2020]. Available from:

https://www.medicines.org.uk/emc/files/pil.6710.pdf
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Information on this page was last updated on 6 Jun 2020

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We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.