Hydralazine

Description

Hydralazine is an antihypertensive medicine used in the treatment of high blood pressure. It is also used after heart valve replacement and in the treatment of heart failure. While using this medicine, it is advised that you get up slowly from a sitting position to avoid falling due to dizziness.

Side effects

Major & minor side effects for Hydralazine

  • Chest tightness
  • Nausea
  • Fast/irregular heart beat
  • Blurred vision
  • Skin rash/itching
  • Dizziness
  • Swelling of feet and lower legs
  • Loss of appetite
  • Weight loss

Uses of Hydralazine

What is it prescribed for?

  • Hypertension
  • Congestive Heart Failure
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its effect is approximately 5-30 minutes depending on the route of administration.
  • Duration of effect
    The time until which this medicine remains active in the body is about 2-8 hours depending on the route of administration.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit forming tendency has been reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. Discuss all the risks and benefits with your doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Discuss all the risks and benefits with your doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to hydralazine.

Coronary heart disease

Hydralazine is not recommended for use in patients with a known history of coronary heart disease.

Rheumatic heart disease

This medicine is not recommended for use in patients with a known history of Rheumatic heart disease.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. Discuss all the risks and benefits with your doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Discuss all the risks and benefits with your doctor before taking this medicine.
General warnings

Systemic lupus erythematosus

Prolonged use of this medicine may increase the risk of systemic lupus erythematosus. The medicine should be discontinued under the doctor's supervision if the patient experiences any unusual reactions.

Missed Dose

If a dose of Hydralazine is missed, take the dose as soon as you remember. If it is almost the time for the next dose, skip the missed dose and take the next dose. Do not double the dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Corticosteroids

Aspirin

Tizanidine

Alprazolam

Diclofenac

Disease interactions

Valvular Heart Disease

The use of this medicine is contraindicated in patients with valvular heart disease due to the increased risk of severe side effects.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Hydralazine only as instructed by the doctor. Do not take larger amounts than prescribed. Seek emergency medical treatment in case of any side effects and do not stop taking this medicine without talking to your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Does not cause sleepiness

How it works
This medicine relaxes and dilates the blood vessels. This allows the blood to circulate freely and smoothly and reduces the blood pressure.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Vasodilators

Schedule

N/A

[Internet]. 2017 [cited 25 July 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/10831

DailyMed - HYDRALAZINE HYDROCHLORIDE- hydralazine hydrochloride injection [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 25 July 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=638a511d-cb51-49b5-b917-ffe8192cc270

Hydralazine - DrugBank [Internet]. Drugbank.ca. 2017 [cited 25 July 2017]. Available from:

https://www.drugbank.ca/drugs/DB01275

Hydralazine: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 25 July 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a682246.html

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Information on this page was last updated on 2 Aug 2017

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.