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Crifos 4 gm Injection

Manufactured byCIPLA LTD
ContainsFosfomycin
Description
Crifos 4 gm Injection is used for the treatment of infections of the bone, respiratory tract, brain, blood, urinary tract, etc. caused by susceptible bacteria.

Side effects

Major & minor side effects for Crifos 4 gm Injection

  • Diarrhea
  • Nausea and vomiting
  • Headache
  • Dizziness
  • Unusual tiredness and weakness
  • Indigestion
  • Visual disturbances
  • Skin rash
  • Increased heartrate
  • Difficulty in breathing

Uses of Crifos 4 gm Injection

What is it prescribed for?

  • Acute Osteomyelitis
  • Complicated Urinary Tract Infection
  • Nosocomial Lower Respiratory Tract Infections
  • Bacterial Meningitis
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to fosfomycin or any other inactive ingredients present along with the formulation.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
General warnings

Drug resistance

Usage of this medicine without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of developing bacteria that are drug-resistant.

Liver impairment

This medicine should be used with extreme caution in patients with liver diseases due to the increased risk of worsening of the patient's condition. Close monitoring of liver function is recommended during treatment with this medicine. Any unusual symptoms should be reported to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Kidney impairment

This medicine should be used with extreme caution in patients with kidney diseases due to the increased risk of worsening of the patient's condition. Close monitoring of kidney function is recommended during treatment with this medicine. Any unusual symptoms should be reported to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Other medicines

This medicine may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Diarrhea

Antibiotic therapy will cause an imbalance in the normal microbial flora of the large intestine, which may promote the growth of a bacteria called Clostridium difficile and you may experience severe diarrhea as a result. Report any such incidence to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Missed Dose

Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of a missed dose is very low.

Overdose

Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Live cholera vaccine

Disease interactions

Colitis

This medicine should be used with caution in patients with gastrointestinal diseases, especially colitis due to the increased risk of worsening of the patient's condition. Close monitoring of the clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Kidney Disease

This medicine should be used with extreme caution in patients with kidney diseases due to the increased risk of worsening of the patient's condition. Close monitoring of kidney function is recommended during treatment with this medicine. Any unusual symptoms should be reported to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.
Food interactions
Information not available.
Lab interactions
Information not available.
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by inhibiting the growth of the bacteria by interfering with the bacterial cell wall synthesis
Legal Status

Approved

Unknown

Approved

Unknown

Classification

Category

Miscellaneous antibiotics

Schedule

Schedule H

Fosfomycin: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2018 [cited 19 September 2018]. Available from:

https://medlineplus.gov/druginfo/meds/a697008.html

Crifos 4 GM Injection [Internet]. CiplaMed. 2019 [cited 5 April 2019]. Available from:

https://ciplamed.com/content/crifos-4-gm-injection

Fosfomycin - DrugBank [Internet]. Drugbank.ca. 2019 [cited 5 April 2019]. Available from:

https://www.drugbank.ca/drugs/DB00828
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Information on this page was last updated on 4 Feb 2020

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